摘要
采用平板菌丝生长抑制法测定了马铃薯糖苷生物碱茄碱和查茄碱、其酸水解产物β1-查茄碱、β2-查茄碱、γ-查茄碱和β2-茄碱及其硫酸化产物6-O-硫酸查茄碱和6-O-双硫酸茄碱的抗真菌活性,分析了糖链组成和结构与其活性的关系。结果表明,糖链的单糖组成、连接方式、连接顺序和单糖数目等对化合物的生物活性均有重要影响。
Potato glycoalkaloids oz-chaconine and α-solanine,the acid-hydrolysis products ,β1-chaconine,β2- chaconine,γ-chaconine and β2-solanine,and the 6-O-sulfated products 6-O-sulfated chaconine and 6-0- disulfated solanine was examined for their percent inhibition on radial growth of fungi using an agar dilution method,and then,the structure-antifungal activity relationships of them was analyzed. Results indicated that the nature,order and number of attachment of the carbohydrate residues of potato glycoalkaloids could strongly influence the antifungal activity.
出处
《食品工业科技》
CAS
CSCD
北大核心
2013年第6期159-163,共5页
Science and Technology of Food Industry
基金
高等学校博士学科点专项科研基金(20070200004)
关键词
马铃薯糖苷生物碱
查茄碱
茄碱
抗真菌活性
构效关系
potato glycoalkaloids, chaconines
solanines
antifungal activity
structure-activity relationship
