摘要
目的探讨药物联合认知行为治疗青少年抑郁症的效果。方法 2006年1月—2008年2月将100例青少年抑郁症患者随机分为药物组和联合组各50例。药物组单纯药物治疗,联合组药物治疗同时给予认知行为治疗,并进行为期1年的观察,分别利用汉密尔顿抑郁量表与症状自评量表进行评定。结果联合组在治疗4、8、12周后与治疗前相比差异均有统计学意义(均P<0.05)。治疗12周后,药物组与联合组汉密尔顿抑郁量表评分分别为(10.44±4.29)、(6.07±3.53)分,差异有统计学意义(P<0.05)。药物组总有效率89.36%,联合组总有效率93.75%,两组比较差异有统计学意义(P<0.05)。1年末随访联合组复发率低于药物组。结论药物联合认知行为治疗对青少年抑郁症效果优于单用药物治疗,且疗效持久、复发率低。
Objective To discuss the clinical efficacy of medication combined with cognitive behavior therapy （CBT） for adolescent depression. Methods From January 2006 to February 2008, 100 cases of adolescent depression were divided into two groups at random： medication group and combination group, 50 cases for each. The former was treated with medication alone, and the latter with medication plus CBT. Both groups were observed for a period of one year and evalu- ated with Hamilton depression scale （HAMD） and symptom checklist. Rrstults After 4, 8 and 12 weeks of treatment, significant difference was found between the two groups. After 12 weeks of treatment, HAMD score was （10.44±4.29） and （ 6.07±3.53 ） respectively in medication group and combination group, which showed significant difference （ P 〈 0. 05）. The total effectiveness rate was 89.36% and 93.75% respectively in medication group and combination group, in which significant difference was found （ P 〈0. 05 ）. At the end of one - year follow - up, combination group had a lower reeurrence rate than medication group. Conclusions Medication combined with CBT is superior to single medication in treating adolescent depression, with long- lasting efficacy and low recurrence rate.
出处
《社区医学杂志》
2013年第4期13-15,共3页
Journal Of Community Medicine
关键词
青少年抑郁症
药物治疗
认知行为治疗
联合治疗
Adolescent depression
Medication
Cognitive behavior therapy
Combined therapy
