摘要
目的:探讨阿尔茨海默病和血管性痴呆患者行为和精神症状的特点及其相关因素。方法:用AD病理行为评分表(BEHAVE-AD)评定41例AD和41例VD患者的BPSD。结果:所有痴呆患者均存在BPSD,发生率为100%,AD与VD患者BEHAVE-AD总分无显著差异(P>0.05)。常见的症状群是日夜节律紊乱(79.3%)、偏执和妄想(43.9%)和行为紊乱(42.7%)。AD组较VD组,攻击行为发生率高(P<0.05)。重度VD较重度AD,情感障碍的发生率高,程度重,P均<0.05。轻中度痴呆的焦虑和恐惧症状发生率较重度患者高(P<0.05)。结论:痴呆患者的BPSD发生率高,不同类型和不同严重度痴呆患者的BDSP呈现不同的特点,应予以关注。
ABSTRACT Objective： To investigate behavioral and psychological symptoms of dementia （BPSD） characteristics and related factors in patients with Alzheimer＇s disease （AD） and vascular dementia （VD）. Methods： BPSD in 41 patients with AD and 41 patients with VD were assessed by the scale of Behavioral Pathology in Alzheimer＇s Disease （BEHAVE-AD）o Results： The incidence of BPSD was 100% in all dementia patients. The difference of total BEHAVE-AD score between two groups was not statistically significant （P 〉0.05）. Circadian rhythm disorders （79.3%）, paranoia and delusions （43.9%） and behavior disorders （42.7%） were the common symptom clusters. Compared with VD group, the incidence of aggressive behavior was higher in AD group （ P 〈 0.05 ） . Compared with severe AD group, both the incidence and the severity of affective disorders in severe VD group were higher （both P 〈0.05）. The symptom cluster of anxiety and fear in mild and moderate dementia patients was higher than those in severe dementia patients （ P 〈0.05 ） . Conclusion： The incidence of BPSD is high in dementia patients. Dementia patients with different type and severity show different characteristics in BPSD, respectively. We should pay attention to these features. KEY WORDS Alzheimer＇s disease; vascular dementia; behavioral and psychological symptoms of dementia
出处
《上海医药》
CAS
2013年第5期32-34,共3页
Shanghai Medical & Pharmaceutical Journal
关键词
阿尔茨海默病
血管性痴呆
痴呆的行为和精神症状
Alzheimer＇s disease
vascular dementia
behavioral and psychological symptoms of dementia
