摘要
目的:探讨肺癌患者血浆血管内皮生长因子(VEGF)水平及其化疗后与CEA变化的相关性。方法:采用酶联免疫吸附法(ELISA)检测30例肺癌患者化疗前后血浆VEGF及CEA水平并进行比较分析。结果:肺癌患者血浆VEGF水平与性别、年龄无关(P>0.05);腺癌、鳞癌、小细胞肺癌三组之间比较,差异无统计学意义(P>0.05)。Ⅱ、Ⅲ、Ⅳ期肺癌患者化疗前三组之间比较,差异具有统计学意义(P<0.05)。化疗后VEGF与CEA变化成正相关(P>0.05))。结论:肺癌患者血浆VEGF水平显著升高,且分期越晚血浆VEGF水平升高越明显;化疗后VEGF与CEA变化成正相关。
Objective ：＇ To evaluate the association and predictive value of blood plasma VEGF levels with CEA after chemotherapy in lung cancer patients. Method： 30 patients were evaluated and analysed.VEGF and CEA levels were measured before after 2 cycles of combination chemotherapy. Result： There was significant difference in blood plasma VEGF between the group of lung cancer in different stage.Conclusion： Levels of plasma VEGF can be residented as a potential predictor in lung cancer.
出处
《中国医学创新》
CAS
2013年第5期15-16,共2页
Medical Innovation of China
