摘要
目的:评价上海地区医院头孢菌素类药的应用现状和趋势。方法:对2009-2011年上海地区119家医院头孢菌素类药的主要品种、销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计、分析。结果:该地区医院头孢菌素类药的销售金额在2010年达到高峰,2011年出现明显下降;口服剂的销售金额呈现小幅增长,注射剂的销售金额有下降趋势;3年来,头孢克洛、头孢克肟和头孢地尼的销售金额在口服剂中排名前3位,头孢呋辛酯、头孢克洛和头孢克肟的DDDs排名前3位,头孢替安、头孢呋辛和头孢西丁在注射剂中占销售金额和DDDs排名的前3位。结论:应继续加强头孢菌素类的临床应用管理,以确保临床用药的有效、安全和经济。
OBJECTIVE: To evaluate the utilization and tendency of cephalosporin antibacterial drugs in hospitals from Shanghai area. METHODS: The utilization of cephalosporins in 119 hospitals of Shanghai area during 2009-2011 was analyzed statistically in respect of main categories, consumption sum, DDDs and DDC, etc. RESULTS: The consumption sum of cephalosporins reached a peak in 2010 and decreased obviously in 2011. The consumption sum of oral cephalosporins showed a small increase and that of injections showed a downward trend. Over the 3 years, cefaclor, cefixime and cefdinir ranked the top 3 in the list of consumption sum; and cefuroxime axetil, cefaclor and cefixime ranked the top 3 in the list of DDDs; cefotiam, cefuroxime and cefoxitin occupied the top 3 in the list of consumption sum and DDDs of injections. CONCLUSIONS: The management of clinical application of cephalosporin antibacterial drugs should continue to be strengthened so as to ensure effective, safe and economical use of drugs in the clinic.
出处
《中国药房》
CAS
CSCD
2013年第10期888-891,共4页
China Pharmacy