摘要
目的探究并分析阿司匹林联合硫酸镁对妊娠高血压的临床治疗效果。方法选取徐州市第三人民医院自2009年8月至2010年8月间收治的妊娠高血压疾病患者90例，随机分成A、B两组，A组患者45例，治疗过程中静脉滴注25％硫酸镁，每天20g，控制滴速1g／h。B组患者45例，治疗过程中在静脉滴注25％硫酸镁，每天20g，控制滴速1g／n的基础上，加口服阿司匹林，每天口服50mg。分析两种不同用药方式的疗效。结果B组患者高血压（86．67％）、水肿（82．22％）、蛋白尿（73．33％）恢复正常的比例较A组患者的高血压（44．44％）、水肿（46．67％）、蛋白尿（42．22％）高（X2值分别为17．7638、12．4138、8．9271，均P〈0．05）。A组妊娠高血压疾病患者治疗后合并妊娠高血压疾病心脏病（31．11％）、肾功能衰竭（28．89％）、脑出血（28．89％）的比例较B组患者的心脏病（4．44％）、肾功能衰竭（2．22％）、脑出血（2．22％）高（X2值分别为10．9459、12．1805、12．1805，均P〈0．05）。结论阿司匹林联合硫酸镁对妊娠高血压的临床治疗效果显著，值得在临床上推广应用。
Objective To discuss and analyze the clinical treatment effects of aspirin combined with magnesium sulfate on gestational hypertension. Methods Totally 90 cases of gestational hypertension admitted at The Third People＇ s Hospital of Xuzhou from August 2009 to August 2010 were randomly divided into group A and group B with 45 cases. Group A received intravenous dripped 20g of 25% magnesium sulfate every day in the course of treatment, and the dripping speed was 1g/h. On the basis of treatment given to group A, group B was given preoral aspirin 50mg per day. The curative effects of two different therapies were analyzed. Results The percentage of patients whose hypertension（86.67% ）, oedema（ 82. 22% ） and proteinuria（73.33% ） recovered normal level in group B was higher than that in group A [ hypertension（44.44% ）, oedema（46.67% ） and proteinuria（42.22% ） （X2 value was 17. 7638, 12.4138 and 8. 9271, respectively, all P 〈 0.05）. The percentage of patients who suffered from pregnancy-induced hypertension heart disease （31. 11% ）, kidney failure （28：. 89% ） and cerebral hemorrhage （28.89%） in group A after treatment was higher than that in group B [ pregnancy- induced hypertension heart disease（4.44% ）, kidney failure（2.22% ）, cerebral hemorrhage（2.22% ） ] （X2 value was 10.9459, 12. 1805 and 12. 1805, respectively, all P 〈 0.05）. Conclusion Aspirin combined with magnesium sulfate haa significant clinical treatment effects on gestational hypertension, and it is worthy of clinical promotion and application.
出处
《中国妇幼健康研究》
2013年第1期74-76,共3页
Chinese Journal of Woman and Child Health Research
关键词
阿司匹林
硫酸镁
妊娠
高血压
aspirin
magnesium sulfate
gestation
hypertension
