摘要
目的对妊娠高血压综合征孕妇血小板参数及常规凝血指标进行观察分析。方法选择妊高征待产孕妇30例(妊高征组),正常妊娠待产孕妇30例(正常妊娠组),正常非妊娠期妇女30例(对照组)作为研究对象。测定3组妇女血小板参数、常规凝血四项(纤维蛋白原浓度、凝血酶原时间、活话部分凝血活酶时间、凝血酶时间)。结果(1)妊高征组血小板平均容积、血小板容积分布宽度和大血小板比率高于对照组及正常妊娠组(P<0.05);(2)常规凝血检查妊高征组与正常妊娠组两组检查结果差异无显著性意义,但除凝血酶时间外与对照组相比差异均有显著性意义。结论妊高征组孕妇血小板参数较正常妊娠组及对照组相比改变有显著性意义,故观察血小板参数对妊高征的诊断及治疗有一定的价值。常规凝血检查在妊高征的诊断及治疗中意义不大。
Objective To study the variation of plstelets and hemostasis parameters in pregnancy induced hypertension （PHI）. Methods Thirty patients with PHI in third-trimester and thirty normal pregnant women in third-trimester were included. At the same time,thirty normal women without pregnancy served as controls. Blood platelets （PLT）, Platelet distribution width （PDW）, mean platclet volume （MPV）, platelet-large cell ratio （P- LCR）, activated partial thromboplastin time（ AFFr）, prothrombin time（FF）, Fib- finogen（Fib） ,thrombin time（TF） were measured. Results （1） The MPV,PDW,P-LCR in PHI were significant higher than normal pregnant women and controls. （2） The hemostasis parameters in PHI and normal pregnant women have significant difference with controis （P 〈 0.05） except TT, but the difference was not significantly in PHI and normal pregnant women （P 〉 0.05）. Conclusion The parameters of platelet were higher in PHI than normal pregnant women and controls, it means platelet play an important role in the pathogenesis and development of PHI.
出处
《中国实验诊断学》
2008年第10期1252-1253,共2页
Chinese Journal of Laboratory Diagnosis
关键词
妊高征
血小板
凝血指标
pregnancy induced hypertension
blood platelets
hemostasis parameters
