摘要
目的研究小剂量低浓度的甲磺酸罗哌卡因注射液复合小剂量的舒芬太尼注射液实施硬膜外阻滞分娩镇痛的镇痛效果以及对产程、分娩方式、母儿的影响。方法选择2011年6月至2012年5月之间在安康市妇幼保健院分娩，经自愿要求签署硬膜外阻滞分娩镇痛知情同意书者共365例作为研究对象（镇痛组）；随机抽取同时期住院条件相似不愿采用硬膜外阻滞分娩镇痛的产妇365例为对照组，分别观察两组的镇痛效果、产程、分娩方式、剖宫产率、缩宫素应用、新生儿窒息及软产道损伤等母儿并发症。结果镇痛组镇痛后疼痛程度明显减低（t=163．130，P〈0．01），且活动不受限，活跃期比对照组明显缩短（t=-12．878，P〈0．01），第二产程两组无差异。镇痛组改剖宫产率明显低于对照组（X2=38．814，P〈0．01）。两组缩宫素应用、新生儿窒息、软产道损伤、产后出血及尿潴留差异均无统计学意义。结论小剂量低浓度的甲磺酸罗哌卡因注射液复合小剂量的舒芬太尼注射液用于硬膜外阻滞分娩镇痛效果好，可缩短产程，无母儿并发症，能促进自然分娩，降低剖宫产率。
Objective To study the effect of small dose low-concentration of ropivicaine mesylate injection and sufentanil injection used in epidural analgesia in labor and their influence on labor, delivery mode and maternal and infant outcomes. Methods From June 2011 to May 2012 365 cases, willing to sign informed consent for epidural analgesia in labor and giving birth in Maternal and Child Health Hospital of Ankang, were selected as study subjects （analgesia group）. Over the same period another 365 cases with similar conditions but not willing to accept epidural analgesia in labor were randomly selected as control group. The＇ analgesia effect, labor process, delivery mode, rate of cesarean section, use of oxytocin and the complications of mothers and infants such as neonatal asphyxia and birth canal injury of two groups were observed. Results The pain degree was relieved significantly after analgesia in analgesia group （t = 163.130, P 〈 0.01 ）, and the active stage was significantly shorter than that of control group （ t = - 12. 878, P 〈 0.01 ）. There was no difference in second stage of labor between two groups. There were fewer cases in analgesia group changing to accept cesarean section （X2 = 38. 814, P 〈 0.01 ）. The differences in oxytocin, neonatal asyphxia, birth canal injury, postpartum bleeding and postpartum urinary retention between two groups were not significant. Conclusion Small dose low-concentration of ropivicaine mesylate injection and sufentanil injection for epidural analgesia in labor is effective, and they can shorten labor stage, eliminate complications of mothers and infants, promote natural vaginal delivery and reduce the rate of cesarean section.
出处
《中国妇幼健康研究》
2013年第1期68-71,共4页
Chinese Journal of Woman and Child Health Research
基金
安康市2011年科学技术研究发展资助项目[安科技成字（2011）21]
关键词
硬膜外阻滞
镇痛分娩
安全性
剖宫产
epidural block
analgesia labor
safety
cesarean section
