摘要
目的观察甲磺酸罗哌卡因复合舒芬太尼用于腰一硬联合分娩镇痛的效果。方法60例初产妇随机均分为2．38mg甲磺酸罗哌卡因＋1．5μg舒芬太尼组（J组）和5tLg舒芬太尼组（S组）。两组均采取蛛网膜下腔注射并留置硬膜外导管镇痛。记录蛛网膜下腔镇痛起效时间、维持时间、注药前、注药后5、10、15、30、60min的视觉模拟评分（VAs）、下肢运动阻滞情况、产程时间、分娩方式、新生儿Apgar评分及产妇不良反应。结果两组产妇均获得良好的镇痛效果，注药后VAS平均为1～3分，运动神经阻滞评分均为0～1分。产程时间、分娩方式和Apgar评分组间差异无统计学意义；J组瘙痒发生率少于S组（P〈0．01）。结论2．38mg甲磺酸罗哌卡因＋1．5μg舒芬太尼蛛网膜下腔注射行腰-硬联合分娩镇痛安全有效。
Objective To observe the effects of ropivacaine mesylate combined with sufentanil for spinal-epidural labor analgesia. Methods Sixty parturients were equally randomized into 2 groups： 2.38 mg ropivacaine mesylate＋1. 5μg sufentanil （group J）and 5μg sufentanil group （group S）. Epidural catheter was placed after subarachnoid administration in the two groups for labor analgesia. The onset time of subarachnoid administration, duration of analgesia, visual analogue scale （VAS） before administration and 5, 10, 15, 30, 60 min after administration, motor block of lower extremities, labor time and method, neonatal Apgar score, and adverse reaction of parturients were recorded. Results Both groups had satisfactory analgesia effect with the average VAS 1- 3 points and the motor nerve block score 0-1 points. Labor time and method and neonatal Apgar score had no difference between the two groups. The incidence of pruritus in group J was lower than group S（P〈0.01）. Conclusion Ropivacaine mesylate 2. 38 mg-1.5 μg sufentanil used in spinal-epidural labor analgesia were safe and effective.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2011年第6期569-571,共3页
Journal of Clinical Anesthesiology
基金
江西省卫生厅科研基金资助项目(20071120)
