摘要
目的评价血清前清蛋白(prealbumin,PA)的测定在小儿脓毒症诊断中的价值;探讨脓毒症患儿血清PA水平与病情严重程度的相关性。方法观察明确诊断为脓毒症及严重脓毒症患儿共56例,同时选择同年龄、同性别普通感染儿童30例作为对照组,比较3组间血清PA水平,同时记录脓毒症和严重脓毒症组的小儿危重病例评分,比较血清PA水平与小儿危重病例评分(PCIS)之间关系。结果严重脓毒症组和脓毒症组血清PA低于普通感染组(P<0.01),并且严重脓毒症组低于脓毒症组(P<0.01)。脓毒症组、严重脓毒症组的PCIS均与血清PA水平呈正相关。结论小儿脓毒症时,检测PA水平有助于疾病早期诊断,血清PA水平能够反映脓毒症患儿病情的严重程度。
Objective To evaluate the diagnostic value of serum prealbumin in children with sepsis;To explore wether the serum prealbumin level correlated with the severity of illness.Methods A total of 56children with sepsis and severe sepsis hospitalized in PICU were enrolled.Meanwhile,30children with common infections with matched age and sex were enrolled as control group.Serum prealbumin level was compared in three groups.Pediatric critical illness scores of children with sepsis were recorded.The relationship between serum albumin level and pediatric critical illness score（PCIS） was compared.Results The serum prealbumin level of children with sepsis were significantly lower than those with common infections（P0.01）,Moreover,The serum prealbumin level of children with severe sepsis were significantly lower than those with sepsis（P0.01）.Correlation analysis was performed between PCIS with PA in sepsis children.There were significantly differences between them（P0.01）.Conclusion The examination of serum PA is helpful to make distinctive diagnosis at early stage and serum PA levels reflect the severity of the disease in children with sepsis.
出处
《福建医药杂志》
CAS
2012年第4期82-84,共3页
Fujian Medical Journal
