摘要
目的了解女性生殖道支原体属感染及与盆腔炎症发生的相关性,并提出相应的预防与治疗措施。方法对258例盆腔炎症患者和60例健康妇女进行了宫颈分泌物支原体属培养,采用支原体属培养、鉴定、药敏一体化试剂盒进行检测,分析两者支原体属感染率的差异。结果盆腔炎症患者中支原体属感染率为76.7%,对照组为23.3%,两组比较差异有统计学意义(P<0.01);在支原体属感染中以解脲脲支原体(Uu)感染率最高为49.6%,其次是Uu和人支原体(Mh)混合感染率为21.3%,Mh感染率最低为5.8%;盆腔炎症妇女Uu和Uu+Mh感染率显著高于正常妇女,经比较差异均有统计学意义(P<0.01);Uu在盆腔炎症患者中的感染率随着年龄增大而降低,分别为<30岁年龄组65.3%,30~40岁年龄组38.5%,>40岁年龄组20.0%,差异有统计学意义(P<0.01),但各年龄组Mh和Uu+Mh感染率差异无统计学意义。结论盆腔炎症发病与支原体属感染有关,Uu感染为盆腔炎症的重要致病因素之一,临床应高度重视年轻盆腔炎症患者的支原体属培养与药敏检测,以便有效治疗和预防盆腔炎症。
OBJECTIVE To understand the correlation between the Mycoplasma infections of female reproductive tract and the pelvic inflammatory disease so as to put forward the corresponding measures of prevention and treatment.METHODS A total of 258 patients with pelvic inflammatory disease and 60 healthy female were performed for Mycoplasma culture with cervical secretions.The Mycoplasma were detected by using the culture,identification,and drug susceptibility testing integrated kit,the difference in the rate of Mycoplasma infections between the two groups was analyzed.RESULTS The Mycoplasma infection rate was 76.7 percent of the patients with pelvic inflammatory disease and 23.3 percent in the control group,the difference was statistically significant(P0.01).Among the Mycoplasma infections,the infection rate of Ureaplasma urealyticum(Uu) was the highest of 49.6%,followed by mixed infection of Uu and Mycoplasma hominis(Mh)of 21.3%,the infection rate of Mh was the lowest of 5.8%.The Uu and Uu+Mh infection rates of the female patients with pelvic inflammatory disease were significantly higher than the normal women,the difference was statistically significant(P0.01).The infection rate of Uu in the patients with pelvic inflammatory disease reduced with the increasing of age,the infection rate of the patients aged less than 30 years old was 65.3%,the patients aged between 30 and 40 years old 38.5%,the patients aged more than 40 years 20.0%,the difference was statistically significant(P0.01).However,the difference in the infection rate of Mh or Uu+Mh between the various age groups was not statistically significant.CONCLUSION The incidence of pelvic inflammatory disease is related to the Mycoplasma infection,Uu infection is one of the most important pathogenic factors for pelvic inflammatory disease,thus it is necessary for the young patients with pelvic inflammatory disease to pay great attention to the Mycoplasma culture and the drug susceptibility testing so as to effectively prevent and treat the pelvic
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第4期855-857,共3页
Chinese Journal of Nosocomiology
关键词
支原体属
盆腔炎症性疾病
女性生殖道
Mycoplasma
Pelvic inflammatory disease
Female genital tract