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口腔矫治器治疗OSAS有效者和无效者的比较

Comparison of responders and non-responders to oral appliance for the treatment of obstructive sleep apnea syndrome
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摘要 目的应用口腔矫治器(OA)治疗阻塞性睡眠呼吸暂停综合征(OSAS)患者,比较有效者和无效者的颅面形态及上气道结构的CT测量指标差异,探讨OA治疗OSAS的效果。方法随机选取采用OA治疗有效及无效的OSAS患者各9例,两组患者在年龄、体质量指数(BMI)、呼吸暂停指数(AHI)相匹配。对两组患者进行CT扫描,分析比较其CT测量指标的差异。结果与治疗有效者相比,治疗无效者的ANB角较小(P<0.05),下颌平面角(SN-MP)、腭咽部的横截面积及腭咽部气道容积则明显增大(P<0.05)。结论使用OA治疗OSAS患者,应注意患者颅面形态和上气道形态,预测其治疗效果,选择合适的治疗方法。 Objective To compare CT variables of craniofacial morphology and upper airway between responders and non-responders to oral appliances(OA) in obstructive sleep apnea syndrome(OSAS) patients,to determine whether pretreatment CT variables can be used to predict therapeutic effects of OA therapy.Methods Nine non-responders were randomly selected for this study.Their individually matched responders were selected and matched for sex,age,body mass index(BMI),and apnea and hypopnea index(AHI).All the patients received computed tomography.CT variables were measured and compared.Results The ANB angle was smaller(P0.05),and SN-MP angle,velopharyngeal cross-sectional area and volume of velopharyngeal were significantly larger in the non-responders(P0.05).Conclusion When treating OSAS patients with OA,clinicians should pay particular attention to craniofacial morphology and airway size,predict the therapeutic effects,and select the appropriate method.
作者 杜林娜 郭泾
出处 《山东大学学报(医学版)》 CAS 北大核心 2012年第8期120-123,共4页 Journal of Shandong University:Health Sciences
关键词 阻塞性睡眠呼吸暂停综合征 上气道 口腔矫治器 体层摄影术 X线计算机 颅面形态 Sleep apnea syndrome Upper airway Oral appliance Tomography x-ray computed Craniofacial morphology
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参考文献21

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