摘要
目的:获取成年无鼾男性人群的上气道及周围组织形态的核磁共振数据,为相关呼吸疾患人群提供对比资料.方法:从453名男性志愿者中选取83名无鼾者,青年组(22～29岁)30人,中青年组(36～45岁)31人,中老年组(46～57岁)22人.所有志愿者在严格固位条件下进行核磁共振扫描.利用核磁共振设备的固有软件及特定公式进行测量和计算.结果:获得上气道各段及周围组织形态的线距、面积和体积共93项测量指标.结论: 建立了3个年龄段的无鼾男性人群上气道及周围组织形态的均值和变异范围.
Objective: To obtain the data about morphology of upper airway and surrounding tissues of non-snoring males from three age groups. Methods: Through questionnaires and clinic examinations, 83 non-snoring males (20-60 years) were selected from 453 volunteers and involved in the following research. There were 30 volunteers aged from 22 to 29 (mean 23.60±2.58 years), 31 volunteers aged from 36 to 45 (mean 40.10±2.64 years) and 22 volunteers aged from 46 to 57 (mean 49.55±3.45 years). Magnetic resonance imaging (MRI) of upper airway of each volunteer was acquired under strict posture-control conditions. The dimensions and cross-section area of nasopharynx, velopharynx, glossopharynx, hypopharynx and whole upper airway with its surrounding tissues were measured with MRI intrinsic software. Volumes of upper airway and surrounding tissues were also calculated. Results: There were 93 items about morphology of the upper airway and surrounding tissues of non-snoring males from the three age groups.With increase in age, some nasopharynx items showed increase tendency, while little change showed in velopharynx, glossopharynx and hypopharynx. Fat volume, tongue volume, anterior and posterior pharyngeal dimension showed age-related increase tendency, but fat deposition rate slowed down in elder age in non-snoring males, which supplies the reason why non-snoring males avoided becoming sleep apnea patients. Conclusion:We provide age-related reference data of upper airway and its surrounding tissues for further sleep and respiration research.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2005年第2期190-194,共5页
Journal of Peking University:Health Sciences
基金
国家自然科学基金(30070822)资助~~
