摘要
目的探讨青岛及周边地区外阴阴道念珠菌病致病菌的菌种特征。方法采用常规念珠菌培养方法鉴定菌种，包括沙氏培养基，血清芽管实验，CHROMagar念珠菌显色培养基及API20CAUX酵母菌鉴定系统。结果2011年5～11月共收集362例妇科门诊患者的阴道分泌物，病原学分析显示，念珠菌阳性例数为313例，总感染率为86．46％，菌种构成分布为白念珠菌275株，光滑念珠菌13株，近平滑念珠菌8株，热带念珠菌7株，克柔念珠菌5株，葡萄牙念珠菌1株，都柏林念珠菌1株，粘质红酵母菌1株，奥默毕赤酵母菌1株，粘性丝孢酵母菌1株。结论白念珠菌仍是外阴阴道念珠菌病的常见致病菌，非白念以光滑念珠菌为主。
Objective To analyze Candida species causing vulvovaginal candidiasis in Qingdao and surrounding areas. Methods Vaginal discharge specimens were collected from 362 patients with suspected vulvovaginal candidiasis in the Affiliated Hospital of Qingdao University Medical College from May 2011 to November 2011, and subjected to routine fungal culture. The Candida isolates were identified by using Sabouraud dextrose agar, CHROMagar medium, germ tube test with serum, and API 20C AUX Clinical Yeast System. Results Totally, 313 （86.46%） Candida strains were isolated from the specimens of 362 patients. Of these Candida strains, 275 were identified as Candida albicans, 38 as non-albicans Candida species, including 13 Candida glabrata strains, 8 Candida parapsilosis strains, 7 Candida tropicalis strains, 5 Candida kmsei strains, 1 Candida lusitaniae strain, 1 Candida dubliniensis strain, 1 Rhodotorula mucilaginosa strain, 1 Pichia ohmed strain and 1 Trichosporon mucoides strain. Conclusions As far as vulvovaginal candidiasis is concerned, Candida albicans is still the most prevalent pathogen, and Candida glabrata appears to be the predominant species in pathogenic non-all3icans Candida species.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2013年第2期128-129,共2页
Chinese Journal of Dermatology
基金
青岛市应用基础科技计划项目（10-3-4-7-9-jch）
