摘要
目的探讨结核性胸膜炎患者血浆和胸腔积液抑瘤素-M(OSM)、肿瘤坏死因子(TNF-α)及干扰素(IFN-γ)水平检测及临床意义。方法采用ELISA检测56例结核性胸膜炎组胸腔积液和血浆OSM、TNF-α及IFN-γ指标水平,并与40例健康对照组血浆中上述指标进行对比分析。结果结核性胸膜炎组血浆的OSM、TNF-α、IFN-γ水平明显升高,与健康对照组血浆相比差异有统计学意义(P<0.05);结核性胸膜炎组中的胸腔积液OSM、TNF-α、IFN-γ水平明显高于血浆中相应检测指标水平,差异有统计学意义(P<0.05)。结论血浆和胸腔积液OSM、TNF-α、IFN-γ指标水平检测对结核性胸膜炎的诊断及病情评估具有重要的临床意义。
Objective To explore the detection on OSM,TNF-α and IFN-γ of plasma and hydrothorax in patients with tuberculous pleurisy and its clinical significance.Methods The OSM,TNF-α and IFN-γ in the plasma and hydrothorax of 56 patients with tuberculous pleurisy group,the OSM,TNF-α and IFN-γ in the plasma of 40 patients with healthy control group were detected by ELISA.These two groups were compared and analyzed.Results Detection on OSM,TNF-α and IFN-γ of plasma in patients with tuberculous pleurisy group were significantly higher than those in healthy control group,the difference was statistically significant（P0.05）;In the tuberculous pleurisy group,detection on OSM,TNF-α and IFN-γ of hydrothorax were significantly higher than those in the plasma of patients,the difference was statistically significant（P0.05）.Conclusion The detection on OSM,TNF-α and IFN-γ of plasma and hydrothorax play an important role in the assessment and treatment of tuberculous pleurisy.
出处
《国际检验医学杂志》
CAS
2012年第24期3002-3003,共2页
International Journal of Laboratory Medicine
关键词
结核
胸膜
生物因子
肿瘤坏死因子Α
干扰素Ⅱ型
tuberculosis
pleural
biological factors
tumor necrosis factor-alpha
interferon type Ⅱ
