摘要
目的探讨老年男性急性冠脉综合征（ACS）患者血清铁蛋白（sF）水平及其临床意义。方法选择本科住院的64例老年男性ACS患者（ACS组）为观察对象；以60例本院门诊复查的稳定劳力型心绞痛患者为心绞痛对照组；以同期60例本院门诊体检者为健康对照组。ACS组于入院后次日清晨、心绞痛对照组及健康对照组体检时采集空腹静脉血，采用化学发光微粒子免疫分析技术测定各组受试者的SF水平。检测ACS组患者的总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）和空腹血糖（FPG）水平，再按血脂和血糖水平不同将ACS患者分为正常组和异常组，分析两组sF水平。结果ACS组患者sF水平（μg／L）明显高于心绞痛对照组及健康对照组（267．79±149．25比193．93±41．71、89．56±49．95，均P〈0．01）；血清TC、TG、LDL及FPG正常组与异常组sF比较差异均无统计学意义（均P〉0．05）；而HDL异常组sF水平明显高于正常组（268．96±160．43比188．94±134．92，P〈0．05），异常组sF≥200μg/L的患者比例较正常组明显增加[60．00％（15／25）比33．33％（13／39），P〈0．05]。结论ACS患者sF水平显著高于健康人群，且对冠心病患者进行sF的监测，有助于对疾病严重程度和预后的判断。
Objective To investigate the level of serum ferritin （SF） in the elderly men with acute coronaPy syndrome （ACS） and its clinical significance. Methods Sixty-four elderly male hospitalized patients with ACS （ACS group）were selected in the observation group, 60 outpatients with stable angina pectoris in the clinic for reexamination were enrolled in the angina control group, and 60 subjects in the same period having undergone physical examination were selected in the healthy control group. In the next morning after admission of the ACS group and during physical examination of the angina and healthy control groups, the fast venous blood was collected and analyzed by chemiluminescent micro-particle immunoassay technique for the determination the SF level in the three groups. In the ACS group, the total cholesterol （TC）, triglycerides （TG）, high density lipoprotein （HDL）, low density lipoprotein （LDL） and fasting blood glucose （FPG） levels were detected, and according to the blood lipid and blood glucose levels, the ACS patients were divided into normal group and abnormal group, and then the SF levels in two groups were analyzed. Results The level of SF （~xg/L） in the ACS group patients was significantly higher than that in the angina and healthy control groups （267.79 ~ 149.25 vs. 193.93 ~ 41.71,89.56 ~ 49.95, both P〈 0.01 ） ; the serum TC, TG, LDL and FPG were divided into normal group and abnormal group, there were no significant differences in the level of SF （all P〉0.05 ） between the two groups, however, in the HDL abnormal group, the SF level was significantly higher than that in normal group （268.96 ± 160.43 vs. 188.94 ±134.92, P〈0.05）, abnormal group SF 〉 200 p.g/L of patients compared to the normal group was significantly increased [60.00% （15/25）vs. 33.33% （13/39）, P〈 0.05 ]. Conclusion In patients with ACS, the level of SF is significantly higher than that in healthy population, and in patients with coronary heart disease, the monitor of ser
出处
《中国中西医结合急救杂志》
CAS
北大核心
2013年第1期48-50,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
老年男性
冠心病
急性冠脉综合征
血清铁蛋白
血脂
Aged men
Coronary heart disease
Acute coronary syndrome
Serum ferritin
Bloodlipids
