摘要
目的：观察老年冠心病患者采用不同剂量阿托伐他汀治疗的临床效果。方法：选取我院2013年1月~2014年6月收治的152例接受不同剂量阿托伐他汀治疗的老年冠心病患者为研究对象,随机分成两组,对照组治疗剂量为10mg,实验组治疗剂量为20mg,对比两组临床治疗效果。结果：实验组TG（mmol/L：1.11±0.42 vs 1.37±0.46）、LDL-C（mmol/L：1.05±0.48 vs 1.64±0.41）、TC（mmol/L：3.28±0.64 vs 4.41±0.63）明显低于对照组,HDL-C水平（mmol/L：1.23±0.38 vs 1.11±0.40）显著高于对照组,且窦性心律维持率（17.10%vs36.84%）高于对照组,差异显著（P〈0.05）。结论：高剂量阿托伐他汀治疗老年血脂正常冠心病患者临床疗效确切,值得临床推广。
Objective：To observe the clinical effect of different doses of atorvastatin on elderly patients with coronary heart disease. Methods：This article made old blood lipids in patients with coronary heart disease who has adopted different doses of atorvastatin treatment in our hospital in January 2013-June 2014 as the research objects, we randomly selected 152 cases and they were divided into two groups. The control group was given a therapeutic dose of 10mg, the experimental was given a therapeutic close of 20mg, and then compared two groups of clinical outcomes. Results：In experimental group, TG （mmol/L：1. 11±0.42 vs 1.37±0.46）, LDL-C（mmol/L： 1.05±0.48 vs 1.64±0.41 ）, TC （mmol/L：3.28± 0.64 vs 4.41±0.63） was significantly lower than the control group, the level of HDL-C （mmol/L：1.23±0.38 vs 1.11±0.40）was significantly higher than that of control group, and the maintenance rate of sinus heart rate （17.10%vs36.84%） was higher than that of control group, difference was significant （P〈0.05）. Conclusion：There is a significant clinical effect that high-dose atorvastatin therapy in old blood lipids in patients with coronary heart disease, and it is worthy of positive promotion and application.
出处
《北方药学》
2015年第2期56-57,共2页
Journal of North Pharmacy
关键词
老年人
冠心病
阿托伐他汀
临床效果
The elderly Coronary heart disease Atorvastatin Clinical effect
