期刊文献+

抗菌肽及其在贝类中的研究进展 被引量:4

Antimicrobial Peptides and Their Research Progress in Mollusk
下载PDF
导出
摘要 贝类缺乏特异的免疫系统,主要由细胞和体液免疫系统抵抗外界病菌的侵袭。抗菌肽是其中一种重要的免疫因子,由于抗菌肽特殊的结构和作用机理,不会像其它抗生素使病菌产生耐药性,因此具有广阔的应用前景。本文主要介绍了抗菌肽的特点、作用机理及贝类抗菌肽的研究进展、应用前景和存在的问题。 Mollusk have no adaptive immunity, which mainly depend on the innate immune system involving cell-mediated and humoral components to recognize and eliminate pathogens. Antimicrobial peptides are an im-portant immune factor. Since their special structure and function mechanism, antimicrobial peptides would not make organism produce resistance like other antibiotics. Thus, it has broad application perspective. This paper mainly introduced the characteristic and function mechanism of antimicrobial peptides, as well as the research progress, application perspective and exiting problems of antimicrobial peptides in mollusk.
出处 《基因组学与应用生物学》 CAS CSCD 北大核心 2012年第6期644-649,共6页 Genomics and Applied Biology
基金 宁波市国际合作项目(2010D10017) 浙江省大学生科技创新活动计划共同资助
关键词 贝类 抗菌肽 生物学特点 作用机理 研究进展 应用前景 Mollusk, Antimicrobial peptides, Biological characteristic, Function mechanism, Research progress,Application perspective
  • 相关文献

参考文献35

  • 1Boman H.G., Nilsson-Faye I., and Paul K, 1974, Insect immunity I. characteristics of an inducible cell-free antibacterial reaction in hemolymph of samia cynthia pupae, Infection and Immu- nity, 10(1): 136-145. 被引量:1
  • 2Breithaupt H., 1999, The new antibiotics: Can novel antibacterial treatments combat the rising tide of drug-resistant infections, Nature Biotechnology, 17:1165-1169. 被引量:1
  • 3Camino G., Marimar C., Antonio F., and Beatriz N., 2007, Anal- ysis of differentially expressed genes in response to bacterial stimulation in hemocytes of the carpet-shell clam Ruditapes decussotus: Identification of new antimicrobial peptides, Gene, 406(2): 134-143. 被引量:1
  • 4Charlet M., Chernysh S., Philippe H., H6tru C., Hoffmann J., and Bulet P., 1996, Innate immunity: Isolation of several cys- teine-rich antimicrobial peptides from the blood of a mol- lusk, Mytilus edulis, The Journal of Biological Chemistry, 271:21808-21813. 被引量:1
  • 5杜卫,刘晓萍,梁惠,王玉贞,王春波.扇贝多肽对淋巴细胞的保护作用和反相液相色谱分析[J].中国海洋药物,2000,19(5):27-29. 被引量:25
  • 6Destoumieux D., Munoz M., Bulet P., and Bachbre E., 2000, Pe-naeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, decapoda), Cell Mol. Li. Fe. Sci., 57(8-9): 1260-1271. 被引量:1
  • 7De Zoysa M., Nikapitiya C., Whang I., Lee J.S., and Lee J., 2009, Abhisin: A potential antimicrobial peptide derived from his- tone H2A of disk abalone (Haliotis discus discus), Fish and Shellfish Immunology, 27(5): 639-646. 被引量:1
  • 8Gonzalez M., Gueguen Y., Desserre G., Lorgeril J., Romestand B., and Bachere E., 2007, Molecular characterization of two isoforms of defensin from hemocytes of the oyster Crassos- trea gigas, Dev. Comp. Immunol., 31(4): 332-339. 被引量:1
  • 9Gueguen Y., Romestand B., Fievet J., Schmitt P., Destoumieux- Garzon D., Vandenbulcke F., Bulet P., and Bachere E., 2009, Oyster hemocytes express a proline-rich peptide displaying synergistic antimicrobial activity with a defensin, Molecular Immunology, 46(4): 516-522. 被引量:1
  • 10黄文树,王克坚,李少菁.甲壳动物抗菌肽研究进展[J].海洋科学,2005,29(2):64-68. 被引量:12

二级参考文献201

共引文献130

同被引文献39

引证文献4

二级引证文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部