摘要
贝类缺乏特异的免疫系统,主要由细胞和体液免疫系统抵抗外界病菌的侵袭。抗菌肽是其中一种重要的免疫因子,由于抗菌肽特殊的结构和作用机理,不会像其它抗生素使病菌产生耐药性,因此具有广阔的应用前景。本文主要介绍了抗菌肽的特点、作用机理及贝类抗菌肽的研究进展、应用前景和存在的问题。
Mollusk have no adaptive immunity, which mainly depend on the innate immune system involving cell-mediated and humoral components to recognize and eliminate pathogens. Antimicrobial peptides are an im-portant immune factor. Since their special structure and function mechanism, antimicrobial peptides would not make organism produce resistance like other antibiotics. Thus, it has broad application perspective. This paper mainly introduced the characteristic and function mechanism of antimicrobial peptides, as well as the research progress, application perspective and exiting problems of antimicrobial peptides in mollusk.
出处
《基因组学与应用生物学》
CAS
CSCD
北大核心
2012年第6期644-649,共6页
Genomics and Applied Biology
基金
宁波市国际合作项目(2010D10017)
浙江省大学生科技创新活动计划共同资助
关键词
贝类
抗菌肽
生物学特点
作用机理
研究进展
应用前景
Mollusk, Antimicrobial peptides, Biological characteristic, Function mechanism, Research progress,Application perspective