摘要
基于锰离子的对比剂在肝脏和神经系统MR中的应用具有独特优势。杂合入锰的纳米颗粒具有较常规纳米颗粒更强的顺磁性。目前基于超敏感的锰纳米颗粒的分子影像越来越受到重视。本文针对含锰对比剂在肝脏、神经系统中的应用以及锰纳米颗粒在MR分子影像学中的应用现状进行综述。
Manganese ion （Mn2＋） is calcium （Ca2＋） analog and is also a paramagnetic material. Manganese ion-based MRI contrast agent possesses unique advantage when it is performed in liver and nervous system. The nanoparticles alloyed with manganese have stronger paramagnetic than conventional ones, and molecular imaging based on ultra-sensitive manganese-doped nanoparticles is arousing more and more attention. Application status of manganese contrast agent in liver, nervous system and MR molecular imaging based on nanoparticles alloyed with manganese were reviewed in this article.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第1期142-145,共4页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金(81071197)
关键词
锰离子
对比剂
铁酸锰纳米颗粒
磁共振成像
Manganese ion
Contrast media
Manganese ferrate nanoparticles
Magnetic resonance imaging
