摘要
目的:比较不同根治性放疗技术对腹膜后淋巴结转移的宫颈癌患者放疗靶区及危险器官剂量学的差异,为临床提供剂量学参考。方法:选取10例腹膜后淋巴结转移拟行根治性放疗的宫颈癌患者,分别制订常规盆腔4野盒式照射+腹主动脉旁淋巴引流区适形照射计划(常规放疗组)和调强放疗计划(IMRT组),比较两者靶区及危险器官受量。结果:IMRT计划PTV适形度优于常规放疗计划,差异具有统计学意义,P<0.05。与常规计划相比,IMRT计划的膀胱D50下降11%,直肠D50下降13%,小肠D50下降20%,脊髓D1cc受照剂量下降16%。结论:对于腹膜后淋巴结转移行根治性放疗的宫颈癌患者来说,IMRT计划较常规盆腔4野照射+腹主动脉旁淋巴引流区5野适形照射计划有明显的剂量学优势。
OBJECTIVE： To study the dosimetric differences of the planning target volume and the organs at risk on the patients with retroperitoneal lymph node metastasis of cervical cancer treated by two different radical radiation plans. METHODS： Ten patients with retroperitoneal lymph node metastasis of cervical cancer were selected and treated with the conventional radiotherapy plan i. e. conventional 4 fields box irradiation of pelvic and 5 fields conformal irradiation of para aortic lymph drainage district,and the intensity modulated radiotherapy plan（IMRT）, respectively. The dosimetric differ ences in the planning target volume and the organs at risk was compared between the two plans. RESULTS： IMRT plan showed a better conformability of PTV（P〈0.05）. Compared with conventional radiotherapy, the received dose of the 50% volume in bladder,the rectum,the small intestine,and the received dose of the Dlcc in spine cord in IMRT plan de creased by 11 %, 13%, 20 % and 16%, respectively. CONCLUSIONS ： For the patients of cervical cancer with retroperitone al lymph node metastasis,IMRT plan has a significant desimetric superiority to the conventional radiotherapy plan,i, e. conventional 4 fields box irradiation of pelvic and 5 fields conformal irradiation of para-aortic lymph drainage district plan.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2012年第20期1572-1575,共4页
Chinese Journal of Cancer Prevention and Treatment
关键词
宫颈肿瘤
放射疗法
计算机辅助
放射治疗剂量
cervical neoplasms
radiotherapy,computer-assisted
radiotherapy dosage
