摘要
目的探讨联合应用痰噬菌体、PPD及血清结核抗体检测在诊断肺结核中的作用。方法以2011年1-12月间收治的符合实验要求的肺部疾病患者567人为研究对象,根据患者病情分为肺结核组及非肺结核组,应用痰噬菌体、PPD及血清结核抗体检测三种方法检查其患病情况,比较其灵敏度、特异度及约登指数间的差异。结果肺结核组在痰噬菌体、PPD及血清结核抗体检测中阳性率较非结核组高,其差异有统计学意义(P<0.05)。在联合应用三种方法后,特异度及约登指数明显高于单独应用。结论联合应用三种方法可以降低误诊率,提高诊断准确性。
Objective To evaluate the value of combined application of sputum bacteriophage,PPD and tuberculin testing in the diagnosis of pulmonary tuberculosis.Methods A total of 567 patients with lung diseases hospitalized in the Dongan County Center for Disease Control and Prevention in 2011 were enrolled and were divided into tuberculosis group and non-tuberculosis group.Mycobacterium tuberculosis was determined in them by sputum bacteriophage,PPD and tuberculin testing.The sensitivities,specificities and Youden＇s indices of the three detection methods were compared.Results The positive rates of Mycobacterium tuberculosis by sputum bacteriophage,PPD and tuberculin testing were remarkably higher in the tuberculosis group than those in the non-tuberculosis group.Combination of the three methods could raise the specificity and Youden＇s index.Conclusions The combined application of sputum bacteriophage,PPD and tuberculin testing can reduce the misdiagnosis rate and improve the accuracy of the diagnosis.
出处
《实用预防医学》
CAS
2012年第12期1889-1890,共2页
Practical Preventive Medicine
关键词
肺结核
诊断
联合应用
Tuberculosis
Diagnosis
Combined application
