摘要
目的:探讨血清EGF及TRACP-5b水平在早期诊断乳腺癌骨转移的应用价值。方法:定量检测75例乳腺癌患者和30例健康女性献血员血清中EGF及TRACP-5b含量,应用SPECT核素骨扫描确定有无骨转移。结果:伴骨转移的乳腺癌患者血清EGF及TRACP-5b水平显著高于非骨转移组,差异有统计学意义(P<0.05)。两组患者的血清EGF及TRACP-5b水平显著高于正常对照组,差异有统计学意义(P<0.05)。结论:联合检测骨转换指标EGF及TRACP-5b在乳腺癌骨转移的早期诊断及病程监测中有重要应用价值。目的:探讨血清EGF及TRACP-5b水平在早期诊断乳腺癌骨转移的应用价值。方法:定量检测75例乳腺癌患者和30例健康女性献血员血清中EGF及TRACP-5b含量,应用SPECT核素骨扫描确定有无骨转移。结果:伴骨转移的乳腺癌患者血清EGF及TRACP-5b水平显著高于非骨转移组,差异有统计学意义(P<0.05)。两组患者的血清EGF及TRACP-5b水平显著高于正常对照组,差异有统计学意义(P<0.05)。结论:联合检测骨转换指标EGF及TRACP-5b在乳腺癌骨转移的早期诊断及病程监测中有重要应用价值。
Objective ：To explore the application value of the VEGF and TRACP-5b level in early diagnosis of bone metastasis tumor from the breast carcinoma. Methods： A total of 75 patients with breast carcinoma and 30 healthy female subjects（normal controls） were included in this study in which the level of EGF and TRACP-5b in serum were detected. Single-photon emission computed tomography （SPECT） radionuclide bone scan was used to confirm whether bone metastasis occurred or not. Results：Compared with the healthy subjects, patients with the bone metastasis group had higher EGF and TRACP-5b level in serum which were significantly different according to the analysis of variance （P〈0.05）. Conclusion： The serum level of total EGF and TRACP-5b have application value in the early diagnosis of bone metastasis tumor from the breast carcinoma.
出处
《甘肃医药》
2012年第12期894-895,共2页
Gansu Medical Journal
