摘要
自噬是真核生物细胞中大分子物质降解的过程。研究表明自噬在病原体侵染中起重要作用,自噬缺失导致病原体形态异常,包括分生孢子形成和发育,有性繁殖及附孢形成和膨压产生等,同时侵染力降低,且不同病原体与侵染有关的自噬类型不同。本研究归纳了自噬在稻瘟病菌、炭疽病菌、禾谷镰孢菌等植物病原体中的作用,分析了自噬缺失与侵染缺陷之间的关系,推测其机制为自噬的缺失导致了营养循环失衡,从而影响病菌的生理功能,进而导致侵染异常。病原体自噬的分子机制、线粒体自噬以及自噬在病原体与宿主互作中的作用可作为今后的研究重点。
Autophagy is a process of bulk degradation that occurs in all eukaryotes. Recent reports lnchcated that autophagy played a vital role during infection of pathogen, and the kind of autophagy involved in changes with pathogen species, defect of autophagy in pathogens resulted in various phenotype, including abnormal conidiation development, conidial germination and sexual reproductive ability, development of appressorium, appressorium turgor generation and pathogenicity. In this paper, the role of autophagy was reviewed in Magnaportbe grisea, Antbracnose and Fusarium graminearum, the relationship of autophagy and pathogenicity were analyzed, suggested that defect of autophagy induced the imbalance of nutrition circulation, affected the physiology of pathogen and then changed the pathology of them. The study in the future should be focused on molecular mechanism of autophagy of pathogen, mitophagy and role of autophagy in interaction of pathogen and host plant.
出处
《中国农学通报》
CSCD
2012年第33期223-227,共5页
Chinese Agricultural Science Bulletin
基金
青年科学基金项目"利用T7噬菌体g10-L序列增强外源蛋白在杜氏盐藻叶绿体中的表达"(31000580)
关键词
自噬
植物病原体
致病力
侵染
分生孢子
autophagy
phytopathogen
pathogen invasion
infection
conidia
