摘要
背景:刘福祥教授自行设计的新型种植体在较短种植体长度上给出了较大骨接触面积,同时考虑到种植体的抗扭转能力、抗侧向力能力,种植体与骨弹性模量的匹配及加工和植入、修复的便易度。目的:观察自主设计的新型种植体植入颌骨后种植体-骨界面Ⅰ型胶原的表达变化,探讨新型种植体与牙槽骨的骨结合能力。方法:拔除成年狼犬双侧下颌前磨牙3个月后,于两侧拔牙位点牙槽骨分别植入新型种植体和圆柱状种植体各2枚。结果与结论:随时间增加两组周围骨组织密度逐渐升高,新型种植体组圆盘结构间出现密度逐渐升高的影像组织。两组种植体-骨界面均有Ⅰ型胶原表达,均于术后4周达高峰,且新型种植体组术后2,4周Ⅰ型胶原平均灰度值均高于圆柱状种植体组(P<0.05)。表明新型种植体植入颌骨后能够取得生物性成功,种植体-骨界面成骨较圆柱状种植体更快,更活跃,骨结合能力更强。
BACKGROUND： The new type implant designed by Professor Liu integrates the character of cylinder implant and blade implant. It is shorter but bigger in contact area. The design of new type implant is considered the torsional capacity, latera force resisting ability, the match of implant and bone elastic modulus, as well as processing and implantation and repair convenience. OBJECTIVE： To investigate the changes of type ] collagen expression in the implant-bone interfaces after implanted to the jawbone, and to explore the combining capacity of the new type implant and alveolar bone. METHODS： All the premolars in the bilateral jaw of six adult dogs were extracted. Three months later,two new type implants and two cylinder implants were implanted to the sockets and divided to the new type implants group and cylinder implants group. RESULTS AND CONCLUSION： The density of the guided bone tissue in the two groups was increased with time. The tissues with gradually increased density in the disk structure of the new type implant group were found. The expression of type I collagen was found in the implant-bone interfaces of the two groups, and both reached the peak at week 4 after surgery. The mean gray value of the new type implant group at weeks 2 and 4 after surgery was higher than that of the cylinder implants group （P 〈 0.05）. These findings suggest that new type implant can achieve success after implanted into the jaw bone due to its special design. The osseointegration of the new type implant is earlier, more active and stronger combining capacity than that of the cylinder implant.
出处
《中国组织工程研究》
CAS
CSCD
2012年第43期7991-7994,共4页
Chinese Journal of Tissue Engineering Research
基金
成都市科技攻关计划资助项目(06YTYB003GX-034)~~
