摘要
目的了解突发性聋的听力学表现及预后的相关因素。方法回顾性分析415例突发性聋患者的听力学检查资料:(1)应用Ordinal回归分析方法,以疗效为观察指标,分析415例患者年龄、听力损失程度、听力图类型、是否伴眩晕、病程以及前庭诱导肌源性电位(VEMP)结果对疗效的影响效应;比较耳蜗电图正常组与异常组的上述相关指标的差别情况;(2)采用Ridit统计分析方法分析不同分组的疗效差别情况。结果不同病程组之间差别具有统计学意义(P<0.01),其中1周以内就诊的R值最小,效果最佳,于21d以后就诊的R值最大,效果最差;不伴眩晕组的R值较小,效果好于伴眩晕组(P<0.01);不同发病年龄组之间差别具有统计学意义(P<0.01),年轻组R值最小,效果最佳,老年组R值最大,效果最差;不同听力损失程度之间差别具有统计学意义(P<0.01),轻度的R值最小,效果最佳,极重度的R值最大,效果最差;不同听力曲线类型之间差别具有统计学意义(P<0.01),其中低频型的R值最小,效果最佳,高频型的R值最大,效果最差;耳蜗电图结果正常与不正常组之间差别具有统计学意义(P<0.01),其中异常组的R值最小,效果最佳,正常的R值最大,效果较差;VEMP结果阴性组与阳性组之间差别具有统计学意义(P<0.01),阳性组预后差。结论 (1)VEMP有可能对突聋的预后有预测作用;(2)耳蜗电图阳性的突聋患者要考虑为内淋巴积液,治疗上可以使用脱水利尿剂、激素等,能够获得较好的预后。
Objective To retrospectively analysize the audiological examination information of 415 cases of sudden deafness patients,and to understand the sudden deafness performance of Audiology and prognostic factors.Methods The ordinal regression analysis was used to analize whether the age of electrocochleogram normal and abnormal group,degree of hearing loss,audiogram type,whether vertigo,course of desease,and the vestibular evoked myogenic potentials results and electrocochleogram results had influence on the efficacy.（2） Ridit analysis was used to analysize the efficacy of the different groups.Results The difference between the groups with different course had statistical significance（P0.01）.Within one week for treatment,R-value is the smallest and the treatment is the best.After 21 days for treatment,R-value is the largest and the efficacy is the worst.In group without vertigo,R-value is smaller and efficacy is better than that of group with vertigo（P0.01）;significant difference existed in different age groups（P0.01）,the young group with the smallest R-value and the best efficacy,while the older group with the largest R-value and the worst efficacy;The difference was statistically significant（P0.01） between different degree of hearing loss groups,the smallest R-value and the best efficacy of mild hearing loss,and the largest R-value and the best efficacy of severe hearing loss;The significant difference existed between different types of hearing curve（P0.01）,smallest R-value and the best efficacy of the low-frequency type,the largest R-value and the worst efficacy of the high-frequency;the difference was statistically significant between EcochG normal and abnormal groups（P0.01）,with smaller R-value of the abnormal group,the better efficacy,the greater R-value and the less efficacy of the normal group;the difference between negative vestibular evoked myogenic potentials group and positive group wasstatistically significant（P0.01）.Conclusion（1） Vestibular induced myogenic potentials
出处
《福建医科大学学报》
2012年第5期350-353,357,共5页
Journal of Fujian Medical University
关键词
突发性聋
前庭诱导肌源性电位
耳蜗电图
sudden deafness
vestibular evoked myogenic potentials
electrocochleogram
