摘要
目的探讨围手术期输血指征评分(POTTS)指导的输血方案是否可安全应用于围手术期血红蛋白水平为6～10 g/dL的患者。方法将围术期(包括术前、术中和术后)Hb可能低于10g/dL的择期手术患者21例,按照序贯法随机分为3组:POTTS指导组(A组,n=7)、10 g组(B组,n=7)及7～10 g指南组(C组,n=7)。A组按照POTTS对患者进行评分,根据评分决定启动患者输血的Hb水平;B组将患者围手术期Hb维持在≥10 g/dL;C组根据麻醉医师和/或外科医师的经验和患者的病情,决定启动患者输血的Hb水平(7～10 g/dL)。研究比较:①3组患者围术期红细胞悬液的输注率;②输入红细胞悬液总量;③严重并发症的发生率;④死亡率。结果 A、B、C3组患者的围术期红细胞悬液输注率分别为42.9%、100%、71.4%;输血总量为0.86±0.40(U)、4.14±0.88(U)、3.14±0.96(U);各组患者均无严重并发症发生,各实验组均无患者死亡。结论围术期输血指征评分能安全有效用于临床工作,且不增加术后围手术期各项并发症的发生率及死亡率。
Objective To evaluate the safety and effectivity of transfusion plan guided by peri - opera-tive transfusion trigger score（POTI＇S） in patients with hemoglobin （Hb） level ranged from 6 to 10 g/ dL. Methods Twenty - one patients were randomly divided into group A （ n = 7 ）, group B （ n = 7 ） and group C （n = 7 ） using the sequential method. Patients in group A received transfusion administration strictly under the guidance of POq^FS. Patients in group B were transfused to keep their peri - operative Hb level at more than lOg/dL, while those in group C received transfusion according to doctors＇experi- ence. The tranfusion rate and amount of RBC suspension in peri - operative period, the incidence of se- vere complications and mortality rate were compared, respectively. Results The transfusion rate in 3 groups were 42.9%, 100% and 71.4% and the transfusion amount were 0.86 ~0.40（ U）, 4.14 ~ 0. 88 （U） and 3.14 ＋ 0.96 （ U）, respectively. In addition, neither severe complications nor any mortality were found in each group. Conclusion POTYS could be safely and effectively used in the clinic and didn t increase the postoperative complication incidence and mortality rate in peri -operative period
出处
《遵义医学院学报》
2012年第4期298-301,共4页
Journal of Zunyi Medical University
基金
卫生部专项资助(NO:201002005)
关键词
围术期
输血指征
评分
安全性
有效性
peri - operative period
transfusion trigger
score
safety
effectivity
