摘要
目的通过对高血压病患者血栓分子标志物变化的分析,为高血压患者的临床治疗提供一定的理论依据。方法回顾性总结了进入我院治疗的92例高血压患者的病例资料,设置为高血压组,另外选取100名在我院健康体检血压正常者的检测资料设为对照组,通过文中对高血压病患者血栓分子标志物的检查方法,检测并比较两组的PT,APTT,TT,PAGT:MAR,t-PA,vWF,FIB,CRP指标。最后用统计学方法比较两组相应指标间的差异是否存在统计学差异性。结果高血压组APTT=28.4±4.62,vWF=127.63±14.31,FIB=3.02±0.53,CRP=4.75±1.41,与对照组数据相比具有显著性差异(P<0.05)。PT,TT,PAGT:MAR,t-PA指标间不存在显著性差异(P>0.05)。结论文中对高血压相关指标的检查对高血压及其并发症的诊断、治疗和病情观察均有重要的临床意义。
Objective To analyze the change in the levels of molecular markers for thrombus in patients with hypertension, and to provide a theoretical basis for the clinical treatment of hypertension. Methods Retrospective analysis was performed on the clinical records of 92 patients with hypertension in our hospital. In addition to the patients (hypertension group), 100 persons with normal blood pressure who underwent physical examination in our hospital were assigned to control group. Both groups were subjected to measurement of indices (PT, APTF, TT, PACT: MAR, t-PA, vWF, FIB, and CRP). The two groups were statistically compared with respect to the indices. Results The hypertension group showed APTT of 28.4±4.62, vWF of 127.63±14.31, FIB of 3.02±0.53, and CRP of 4.75±1.41, with significant differences from those of control group (P〈0.05). There were no significant differences in PT, TT, PAGT: MAR, and t-PA between the two groups (P〉0.05). Conclusion The hypertension-related indices are of great clinical significance for the diagnosis, treatment, and monitoring of hypertension and its complications.
出处
《心血管病防治知识(学术版)》
2012年第6期11-12,共2页
Prevention and Treatment of Cardiovascular Disease
关键词
高血压病
血栓分子
标志物
Hypertension
Thrombus
Molecular marker