摘要
目的探讨本地区新生儿高胆红素血症的病因,为预防及治疗提供依据。方法将66例高胆红素血症患儿分为换血组(33例)与未换血组(33例)进行病因分析,并对两组患儿的临床特点进行比较。结果两组高胆红素血症的病因均以溶血性因素为首,占62.1%(41例),感染因素占22.7%(15例),原因不明占15.1%(10例)。两组患儿在总胆红素浓度、发现黄染时间、就诊时间和黄疸持续时间等方面进行比较,差异有统计学意义(P<0.001)。结论溶血与感染是新生儿高胆红素血症的主要原因,总胆红素浓度过高和干预延迟是引起高胆红素血症的高危因素。加强宣传,出院后的随访和及时就诊,是减少胆红素脑病发病的关键。
Objective To discuss the pathogenesis of neonatal hyperbilirubinemia in our region,in order to provide basis for prevention and treatment.Methods The pathogenesis of 66 cases of hyperbilirubinemia children who were divided into exchange transfusion group （n=33） and without exchange transfusion group （n=33） were analyzed,and the clinical features of the two groups were compared.Results The pathogenesis of hyperbilirubinemia in the two groups were the hemolytic factor,infection factor and reason unknown,which accounted for 62.1% （41 cases）,22.7% （15 cases）,15.1% （10 cases） respectively.The total bilirubin concentration,stained yellow find time,visiting time and jaundice duration time were compared between the two groups,the differences were statistically significant （P 0.001）.Conclusion Hemolysis and infection are the main reasons of neonatal hyperbilirubinemia.The high level of total bilirubin concentration and the intervention delay are the risk factors of hyperbilirubinemia.Strengthening propaganda,post-discharge of follow-up and timely treatment are the key of reducing the incidence of bilirubin encephalopathy.
出处
《中国当代医药》
2012年第21期40-41,共2页
China Modern Medicine
关键词
新生儿
高胆红素血症
病因
临床分析
Neonatus
Hyperbilirubinemia
Pathogenesis
Clinical analysis
