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前庭基因治疗研究进展 被引量:1

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摘要 前庭功能障碍可由病毒感染、药物、遗传因素、自身免疫性疾病等多种不同的病因导致,而毛细胞损伤几乎是其共同的病理过程。哺乳动物前庭毛细胞损伤后缺乏有效、完全的自我再生能力。尽管在外周前庭损伤之后,人体能够通过一定的中枢代偿机制逐渐恢复,但这种代偿过程缓慢且程度参差不齐。尤其是对于双侧前庭损伤的病例,中枢代偿作用有限。助听器或人工耳蜗可以替代一部分耳聋患者的听功能,与其相比,迄今为止还没有一种人工装置可以弥补前庭功能的缺失。因此,找到一种行之有效的方法恢复患者的前庭结构与功能显得尤为重要。
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2012年第11期958-960,共3页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金 国家自然科学基金(81100717)
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参考文献27

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