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感音神经性耳聋基因治疗的新进展 被引量:2

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摘要 感音神经性耳聋严重影响了人类健康和生存质量,目前仍无确切有效的治疗方法。随着基因工程技术的发展,基因治疗为攻克这一顽症带来了新希望。基因治疗指将外界正常或治疗基因,通过载体转移到人体的靶细胞,进行基因修饰和表达,从而改善疾病的一种治疗手段。1996年,基因治疗技术首次应用于耳聋的治疗研究,10余年来发展迅速。我们就感音神经性耳聋基因治疗常用的载体、常用的外源基因和载体导入内耳的途径等相关问题综述如下。
出处 《中华医学杂志》 CAS CSCD 北大核心 2007年第40期2873-2875,共3页 National Medical Journal of China
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