摘要
目的探索放疗配合化疗在恶性胶质瘤术后治疗中的临床应用价值。方法选择2006年1月～2011年1月我科就诊的65例恶性胶质瘤术后患者,机械抽样随机将其中的42例分为观察组,采用放疗+化疗,余23例为对照组,采用放疗。结果观察组缓解率为88.1%,3年生存率为47.6%,均高于对照组(P<0.05);胃肠道反应、脑水肿加重及骨髓抑制发生率两组差异无统计学意义(P>0.05)。结论放疗配合化疗不但可显著改善近期疗效,也可显著提高远期疗效,且较为安全。
Objective To explorer the clinical application value of radiotherapy combined with chemotherapy on treatment of patients after malignant glioma.Methods 65 cases of patients with malignant glioma that were treated in our department between January 2006 and January 2008.42 cases of patients were mechanical sampling randomly divided into observation group,and the remainder into control group.Observation group were treated by radiotherapy combined with chemotherapy,and control group by radiotherapy.Results The remission rate of observation group was 88.1% and 3-year survival rate was 47.6%,significantly higher than control group（P0.05）.The difference of incidence of gastrointestinal tract,brain edema and bone marrow suppression wasn＇t significant（P0.05）.Conclusion Radiotherapy combined with chemotherapy can significantly improve not only short-term effect,but also long-term efficacy,and safer.
出处
《四川医学》
CAS
2012年第10期1776-1777,共2页
Sichuan Medical Journal
关键词
恶性胶质瘤
放疗
化疗
malignant glioma
radiotherapy
chemotherapy
