摘要
用2-氨基-5-巯基-1,3,4-噻二唑与1,3-二溴丙烷和一系列苯甲酰基异氰酸酯反应,合成了7种未见文献报道的芳甲酰基脲,并用元素分析、红外光谱和核磁共振氢谱对化合物进行了表征。合成目标化合物的最佳反应温度为40℃,最佳反应时间为4 h,最佳投料比为1.0∶1.0,产率63.5%;生物活性实验证明,该类化合物具有明显的植物激素活性。
Seven new bis-ureas of thiadiazloe derived from 2-amino-5-mercapto-1,3,4-thiadiazole, 1,3-dibromopropane and acyl azides were synthesized and characterized by the physical constants, elementary analysis, IR, and t HNMR. The optimal conditions for preparation of bis-ureas of thiadiazloe were as follows ： n （ bis-ureas of thiadiazloe） ： n was 1.0： 1.0, and the reaction time was 4 h at 40 ℃ ,The product yield of bis-ureas of thiadiazloe could reach 63.5%. The results of bi- olofical activity tests showed that all samples have activity on plant growth hormone and auxin.
出处
《化学试剂》
CAS
CSCD
北大核心
2012年第11期982-984,998,共4页
Chemical Reagents
基金
湖北省教育厅重点项目(D20111902)
湖北省高校校企合作资助项目(XD20100686)
