摘要
目的:探讨不同程度宫颈病变的相关危险因素。方法:对内蒙古某医院妇科门诊进行宫颈活检的673例妇女进行流行病学调查。利用无序多分类Logistic回归模型,分析宫颈上皮内瘤样变(CINⅠ～CINⅢ)、宫颈癌的危险因素。结果:经单因素分析显示,避孕方法、生育次数、清洗外阴频率、接触性出血等7个因素与宫颈病变程度相关。以宫颈炎为对照组,多因素Logistic回归分析发现,生育次数≥2次、宫颈肥大和相关知识知晓率低(OR值分别为7.643、11.957和5.697)是宫颈癌的危险因素;分泌物异味、接触性出血(OR<1)是CIN(Ⅰ～Ⅲ)的保护因素。结论:宫颈癌的发生、发展与生育次数、宫颈肥大、知晓相关知识等因素具有相关性。因此,要重视人群健康宣教,普及妇科知识;建立完整的筛查系统,及早发现癌前病变,有效控制宫颈癌的发生。
Objective： To explore the related risk factors of different degrees of cervical lesions. Methods： An epidemiological investigation was conducted among 673 women who received cervical biopsy in gynecological department of a hospital in Inner Mongolia. Disorder multinomial Logistic regression model was used to analyze the risk factors of cervical intraepithelial neoplasia （CIN） Ⅰ-Ⅲ and cervical cancer. Results： Univariate regression analysis showed that seven factors （ contraceptive methods, the number of delivery, the frequency of cleaning vulva, contact bleeding, and so on） were correlated with the degree of cervical lesions. The cases with cervicitis were selected as control group, multivariate logistic regression analysis found that the number of delivery≥2, cervical hypertrophy, and low awareness rate of CIN Ⅰ-Ⅲ. Conclusion： The occurrence and development of cervical cancer were correlated with the number of delivery, cervical hypertrophy, and the awareness rate of related knowledge. Thus, to control the occurrence of cervical cancer effectively, health propaganda and education among the population should be paid more attention to, the gynecological knowledge should be popularized, a complete screening system should be established, and cervical precancerous lesions should be detected early.
出处
《中国妇幼保健》
CAS
北大核心
2012年第31期4936-4939,共4页
Maternal and Child Health Care of China
关键词
宫颈癌
宫颈上皮内瘤变
宫颈炎
危险因素
Cervical cancer
Cervical intraepithelial neoplasia
Cervicitis
Risk factors
