摘要
目的探讨20岁以上正常成人海马体积(HV)分部磁共振成像(MRI)定量分析方法及确定HV的正常值范围。方法采用3.0T MRI对25例(男性13例,女性12例)受试者行垂直于海马长轴的斜冠状位海马薄层(1.5 mm)扫描,在T1加权相上将海马分为头、体、尾三部并测定HV,包括海马头(HHV)、海马体(HBV)、海马尾(HTV)及整个海马体积(HCV)。结果正常成人HV测量结果:右侧HHV为(1 712.81±242.26)mm3,左侧HHV为(1 640.86±208.70)mm3;右侧HBV为(1 126.59±133.10)mm3,左侧HBV为(1 098.20±145.00)mm3;右侧HTV为(231.22±76.28)mm3,左侧HTV为(229.52±78.39)mm3;右侧HCV为(3 078.62±254.82)mm3,左侧HCV为(2 979.69±227.25)mm3。左右两侧HTV比较差异无统计学意义(P>0.05);右侧HHV、HBV和HCV均大于左侧,差异有统计学意义(均P<0.05)。男女受试者左右两侧HV比较,差异均无统计学意义(均P>0.05)。结论 MRI能对正常成人HV进行定量分析并确定HV的正常值范围。
Objective To investigate the quantitative magnetic resonance imaging(MRI) analysis of parts of hippocampal volume(HV),and to determine the normal range of HV.Methods Twenty-five subjects(13 males and 12 females) underwent a 3.0T MRI with oblique coronal thin sections(1.5 mm) oriented perpendicular to the hippocampal long axis.The hippocampus was divided into three parts of head,body and tail,and the HV including the hippocampal head volume(HHV),hippocampal body volume(HBV),hippocampal tail volume(HTV) and whole hippocampal volume(HCV) were measured on T1-weighted imaging.Results The right-side HHV,HBV,HTV and HCV were(1 712.81±242.26) mm3,(1 126.59±133.10) mm3,(231.22±76.28) mm3 and(3 078.62±254.82) mm3 respectively,and the left-side ones were(1 640.86±208.70) mm3,(1 098.20±145.00) mm3,(229.52±78.39) mm3 and(2 979.69±227.25) mm3 respectively.There was no significant difference between left-side HTV and right-side HTV(P0.05),and the right-side HHV,HBV and HCV were significantly larger than the left ones(P0.05 for all).There was no significant difference in left-side and right-side HV between males and females(P0.05 for both).Conclusion MRI can quantitatively analyse HV,and determine the normal range of HV in normal adults.
出处
《上海交通大学学报(医学版)》
CAS
CSCD
北大核心
2012年第10期1321-1325,共5页
Journal of Shanghai Jiao tong University:Medical Science
基金
上海市科委基金(11ZR1421800)
上海交通大学医学院Med-X基金(YG08PETZD05)~~
关键词
海马体积
磁共振成像
定量分析
hippocampal volume
magnetic resonance imaging
quantitative analysis