摘要
目的:分析咪达唑仑与芬太尼合用在ICU患者镇静中的效果。方法:笔者所在医院2010年5月-2012年5月ICU机械通气患者90例随机分为观察组和对照组,观察组(咪达唑仑和芬太尼组)45例,对照组(芬太尼组)45例,观察两组治疗前后平均动脉压、心率、药物起效时间、不良反应等。结果:观察组药物起效时间及恢复时间均明显短于对照组,比较差异有统计学意义(P<0.05),两组治疗后比较,平均动脉压、心率、血氧饱和度无明显变化(P>0.05)。结论:咪达唑仑与芬太尼合用于ICU患者镇静效果满意,值得临床推广。
0bjective:To analyze the sedative effect of midazolam and fentany on patients in ICU.Method:Ninety patients with ICU mechanicalventilation were randomly divided into observation group and control group from May 2010 to May 2012,observation group (midazolam and fentany)with 45 cases and control group (fentany) with 45 cases,before and after the treatment were observed for arterial blood pressure,heart rate,drug onsettime,adverse reactions and so on.Result:The drug onset time and recovery time in observation group are obviously less than in control group,there wassignificant difference(P0.05),the two groups compare after treatment,arterial blood pressure,heart rate and oxygen saturation have no significantchange(P0.05).Conclusion:Midazolam an d fentany Can provide satisfactory sedation for ICU patients and worthy of clinical.
出处
《中国医学创新》
CAS
2012年第29期53-54,共2页
Medical Innovation of China
关键词
咪达唑仑
芬太尼
镇静
机械通气
Midazolam
Fentany
Sedation
Mechanical ventilation