摘要
近年来研究表明长期暴露在高原低氧环境下严重影响成年男性生殖健康,导致精子浓度的降低,而且这种影响随着海拔高度的增加而加重。导致男性精子浓度降低这一结果的产生与高原低氧环境下精子发生减少、精子DNA的损伤、精子凋亡增加及生殖激素水平的变化等密切相关。本文就国内外关于高原低氧环境影响男性精子浓度的机制研究进展做一综述。
Recent studies show that long exposure to high altitude and hypoxia can seriously affect men’s reproductive health by reducing their sperm concentration,which decreases with the increase of altitude.High altitude and hypoxia are strongly associated with spermatogenic reduction,sperm DNA damage,sperm apoptosis,and decreased level of sex hormones.This article reviews the mechanisms of high altitude and hypoxia affecting sperm concentration.Natl J Androl,2012,18(9): 835-839
出处
《中华男科学杂志》
CAS
CSCD
2012年第9期835-839,共5页
National Journal of Andrology
基金
兰州军区医药卫生科研基金(CLZ11JB09)~~
关键词
高原低氧环境
精子浓度
精子生成
high altitude and hypoxia; sperm concentration; spermatogenesis;