摘要
目的了解并探讨肺结核患者并发呼吸道感染的病原菌分布及耐药性。方法对医院2009年1月-2010年12月住院的肺结核患者送检的合格痰标本做细菌培养和药敏试验,并进行统计分析。结果共分离出161株病原菌,其中革兰阴性杆菌108株占67.1%,革兰阳性球菌34株占21.1%,真菌19株占11.8%;革兰阴性杆菌中前3位依次为肺炎克雷伯菌、阴沟肠杆菌、大肠埃希菌,分别占37.9%、16.1%、8.1%,革兰阳性球菌中前3位依次为金黄色葡萄球菌、表皮葡萄球菌、溶血葡萄球菌,分别占6.8%、4.4%、3.7%;不同病原菌对常用抗菌药物呈现不同程度的耐药。结论肺结核患者并发呼吸道感染的病原菌以革兰阴性杆菌多见,最常见为肺炎克雷伯菌,且细菌耐药性较高,应加强病原菌的检测及耐药性监测,合理使用抗菌药物。
OBJECTIVE To investigate the effect of the operation time on the clinical treatment of preauricular fistula combined with fungal infections.METHODS A total of 64 patients who received treatment of preauricular fistula combined with fungal infections from Oct 2009 to Oct 201l were selected as research objects and randomly divided into the operation infection group and the operation infection control group,with 32 cases in each.RESULTS There were 12 patients in the operation infection control group with removal of stitches within 4-6 days,accounting for 37.50%,significantly higher than 12.50% of the operation infection group,（P0.05）,however,there were 11 patients with the removal of stitches within 8-10 days,accounting for 34.37%,significantly lower than 56.25% of the operation infection group（P0.05）;the cure rate of the operation infection control group was 96.88%,the recurrence rate 3.12%,the cure rate of the operation infection group was 93.75%,the recurrence rate 6.25%,as compared with the two groups,the differences in the cure rate and the recurrence rate were not statistically significant.CONCLUSION The patients of preauricular fistula combined with fungal infections should undergo the surgery under the basic control of the inflammation as soon as possible,and it can not only increase the therapeutic effect of surgery and shorten the time of stitches removal,without affecting the cure rate and the recurrence rate,but also can shorten the course of treatment and reduce the burden for the patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第19期4407-4409,共3页
Chinese Journal of Nosocomiology
关键词
肺结核
病原菌
耐药性
Preauricular fistula
Fungal infection
Clinical analysis
