摘要
目的了解广东省深圳市自然人群中戊型肝炎病毒抗体(抗-HEV)IgG感染情况,为戊肝防控工作提供科学依据。方法采取多阶段整群随机抽样方法,于2010年7—8月在深圳市抽取2个区调查1～59岁各年龄组自然人群共计3 771人,采集静脉血,用酶联免疫吸附试验(ELISA)检测抗-HEV IgG,并应用SPSS 16.0软件对结果进行分析。结果深圳市自然人群中HEV总感染率为23.68%(893/3 771),其中男性为23.72%(435/1 834),略高于女性的23.64%(458/1 937),差异无统计学意义;随居民年龄增长阳性率呈不断增高的趋势(χ2趋势=472.59,P<0.05);罗湖区阳性率为19.40%(413/2 129),低于宝安区的29.23%(480/1 642),差异有统计学意义(χ2=49.603,P<0.05);不同职业人群中,农民的戊肝感染率最高,为43.40%(23/53);小学学历人群戊肝感染率最高,为46.52%(87/187)。结论深圳市自然人群中存在较高程度的戊型肝炎病毒感染。
Objective To explore seroprevalence of anti-hepatitis E virus（HEV） IgG among the population in Shenzhen and to provide evidence for the prevention and control of hepatitis E.Methods Multi-stage random cluster sampling was used to select subjects aged over one year from general population in Shenzhen.All subjects were interviewed with a questionnaire and their venous blood specimens were collected for anti-HEV IgG test with enzyme-linked immunosorbent assay（ELISA） kits.The data were analyzed with SPSS 16.0 software.Results The crude seroprevalence of anti-HEV IgG was 23.68%（95% confidence interval：22.33%-25.04%） among the subjects.The positive rate of man（23.72%） was slightly higher than that of woman（23.64%） without significant difference.There was an increasing trend in the prevalence with the age.The prevalence was lower in the subjects of Luohu district than that in Baoan district（χ2=49.603,P0.05）.The prevalence in the farmers was the highest among the subjects of different occupations.The subject with the education of primary school had the highest seroprevalence.Conclusion In general,the seroprevalence of anti-HEV IgG is relatively high among the population in Shenzhen.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2012年第10期1286-1288,共3页
Chinese Journal of Public Health
基金
国家科技重大专项"十一五"课题(2009ZX10001-018)
