摘要
目的探讨中毒性表皮坏死松解型药疹(TEN)大面积松解患者的皮肤黏膜治疗方式。方法 4例TEN住院患者均采用纳米银抗感染敷料联合无菌棉垫覆盖创面,观察治疗效果。结果 4例均未发生皮肤黏膜感染,3例15 d后痊愈出院,皮肤恢复良好,无疤痕、无色素沉着,1例因多器官功能衰竭、消化道大出血死亡。结论纳米银抗感染敷料具备良好通透性、能有效吸收渗出液、维持伤口适宜湿度、预防和控制感染、减少换药以及加速创面修复进程等优势,对肝脏和肾脏功能各项指标无影响,值得临床推广应用。
【Objective】 To explore the treating methods of skin mucosa for TEN epidermolysis and exfoliative patients in large area.【Method】 Four TEN hospitalized patients are applied with the combination of nano-silver ion dressing and sterile pad to covering the wound and observe the effect.【Results】 All four cases don＇t get any skin mucosa infection and three of them are discharged from hospital after 15 days with good recovery of their skins and no scars or pigmentation.One case died for multiple organ failure and massive gastrointestinal hemorrhage.【Conclusion】 The anti-infected nano-silver dressing has the advantage of good permeability and can absorb exudate effectively so as to maintain the appropriate humidity for the wound,prevent and control the infection,reduce dressing,accelerate the wound repair process and it also has no effect on various indicators of liver and kidney,worthy of clinical application.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2012年第24期79-82,共4页
China Journal of Modern Medicine
