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阿托伐他汀钙对肾病综合征高脂血症及蛋白尿的影响研究 被引量:5

Effects of Atorvastatin Calcium on Hyperlipidemia in Nephritic Syndrome and Proteinuria
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摘要 目的观察阿托伐他汀钙对原发性肾病综合征高脂血症的影响。方法将原发性肾病综合征患者50例随机分为两组。对照组24例,给予标准激素治疗;治疗组26例,在标准激素治疗的基础上加用阿托伐他汀钙。治疗2周后分别观察两组患者血脂、尿蛋白定量、血清白蛋白的情况。结果治疗组治疗2周后,患者血脂水平下降明显,与对照组比较差异有统计学意义(P<0.05)。结论阿托伐他汀治疗原发性肾病综合征高脂血症起效快、安全性好。 Objective Effects of atorvastatin calcium on prlm,ry nephrotic syndrome with hyperlipidemia in rats. Methods Prlmary nephrotic syndrome a report or 50 cases, Were randomly divided into two groups, A control group of 24 cases, Given the standard hormone therapy; The treatment group of 26 cases, In the standard hormone therapy combined with ator- vastatin calcium. After 2 weeks of treatment were observed in two groups of patients with blood lipid, The quantity of urinary pro- tein, Serum albumin. Results The treatment group after 2 weeks treatment, Levels of serum lipid in patients with decreased obviously, Compared with the control group there were significant differences (P 〈0. 05). Conclusion Effect of atorvastatin in treatment of primary nephrotic syndrome hyperlipemia fast effect, good safety.
作者 韦凤华
出处 《临床合理用药杂志》 2012年第30期5-6,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 阿托伐他汀钙 肾病综合征 高脂血症 Atorvastatin calcium Nephritic syndrome Hyperlipidemias
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