摘要
目的 探讨小儿肾病综合征脂代谢异常的特点和临床意义。方法 对 32例原发性肾病综合征 (肾病组 )和 33例急性肾小球肾炎的血脂变化与无肝、肾疾病的对照组对比分析 ,并观察肾病综合征患儿的心肌酶谱变化。结果 肾病组患儿均有明显的脂代谢异常 ,其血脂各项指标与对照组比较有显著性差异 ,其心肌酶谱有不同程度异常变化。结论 小儿肾病综合征时广泛存在脂代谢异常 ,以胆固醇 (CHO)、载脂蛋白 B (APOB)、低密度脂蛋白(L DL)等增高明显 ,对可能导致动脉硬化 ,加重肾损害 ,引起冠心病的脂质成分应重视并追踪观察。
Objective] To investigate the characteristic and clinical significance of abnormal lipometabolism in children’s nephrotic syndrome. To investigate the characteristic and clinical significance of abnormal lipometabolism in children’s nephrotic syndrome. The changes of serum lipids of 32 cases of primary nephrotic syndrome,33 cases of acute glomerulonephritis and controls with no liver and kidney diseases were analyzed.The myocardial enzymogram were also detected in children’s nephrotic syndrome. Nephrotic syndrome children had significantly abnormal lipometabolism.Their lipid levels had significant difference contrast with control group.The myocardial enzymogram abnormal changed with different degrees.[Conclusion] Children’s nephrotic syndrome have abnormal lipometabolism widely.It is include cholesterol(CHO),apolipoprotein B(APOB)and low density lipoprotein(LDL)increase significantly.It maybe induce to arteriosclerosis more renal injuries and coronary heart disease.We should pay attention to it and observed it periodically.
出处
《福建医药杂志》
CAS
2004年第3期15-17,共3页
Fujian Medical Journal
