摘要
目的探讨D-二聚体(D-D)与纤维蛋白(原)降解产物(FDP)的检测结果在冠心病(CHD)患者中的临床应用价值。方法对52例急性心肌梗死(AMI)患者、48例不稳定性心绞痛(UAP)患者、42例稳定性心绞痛(SAP)患者,采用ACL900全自动血凝仪,通过胶体免疫比浊法定量检测血浆中D—二聚体与纤维蛋白(原)降解产物的含量,并与40例正常对照者进行对照,探讨其临床应用价值。结果血浆D-D和FDP含量及阳性检出率,AMI组比UAP组、SAP组和正常对照组明显升高,差异有统计学意义(P<0.01);UAP组比SAP组和正常对照组明显升高,差异也有统计学意义(P<0.01);SAP组比正常对照组略有升高,但差异无统计学意义(P>0.05)。结论血浆中D-D和FDP的含量可作为AMI的诊断指标及UAP和SAP的鉴别诊断指标,D-D和FDP联合检测更有助于提高冠心病的诊断。
Objective To study the clinical application value of D-dimer （D-D） and fiber protein （former） degradation products （FDP） in the coronary heart disease （CHD）. Methods D-D and FDP were tested by immunonephelometry in AMI, UAP and SAP. The results were analyzed by statistics. Results The levels of D-D and FDP of group AMI are higher than its of UAP,SAP and normal group, as well as there are significant difference（P〈0.01）. The levels of D-D and FDP of group UAP are higher than its of SAP and normal group, as well as there are significant difference（P〈 0.01）. The levels of D-D and FDP of group SAP are higher than its of normal group, however, there are no significant difference（P〉0.05）. Conclusion D-D and FDP can be used in the diagnosis of coronary heart disease, and they can help diagnosis of coronary heart disease.
出处
《西部医学》
2012年第9期1794-1796,共3页
Medical Journal of West China
关键词
冠心病
急性心肌梗死
心绞痛
纤维蛋白原降解产物
D-二聚体
Coronary heart disease Myocardial infarction Angina pectoris Fibrinogen degradation products Ddimer
