摘要
目的:为儿科临床合理用药提供参考。方法:通过检索儿科用药药品分剂量的相关文献,结合临床用药的经验,从剂型、品种、包装、规格、可替代药品等方面,对分剂量的不同策略进行实例分析。结果:药品分剂量的策略包括液体制剂替代固体制剂,片剂中尽量选择有刻痕、胶囊型、直径较大的品种,选用容易分剂量的包装,选用规格小的包装,选用可替代且容易分剂量的药物等。结论:药品分剂量的策略灵活多样,需要全面考虑药品的剂型、生产工艺、包装、规格等多种因素,必要时可选用可替代的其他药物或制备临用制剂以弥补儿童专用剂型的匮乏。
OBJECTIVE： To provide reference for rational use of pediatrics drugs. METHODS： By retrieving related literatures about subdivision of pediatric drugs, based on the experience of clinical drug use, examples of different strategies for subdivision were analyzed in terms of dosage form, species, types, packages, specification and replaceable drugs, etc. RESULTS ： The strate- gies for dose splitting were as follows, such as liquid preparation replaced solid preparation; types of tablet were nick type, cap- sule type, large diameters type as far as possible; it is suitable to select package being easy to subdivide, small specification of package and replaceable drugs which were easy to subdivide. CONCLUSIONS： The strategy for dose dividing is various, so dos- age forms, manufacturing technology, package and specification should be all taken into consideration. Sometimes, it is necessary to purchase replaceable drugs or prepare extemporaneous preparations in order to retrieve the deficiency of licensed pediatric medicines.
出处
《中国药房》
CAS
CSCD
2012年第37期3537-3539,共3页
China Pharmacy
关键词
儿科药品
分剂量
策略
合理用药
Pediatric drug
Dose dividing
Strategy
Rational use of drugs
