摘要
采用四氯化碳引起的肝损伤动物模型,对灵芝茯苓提取物组方的保肝作用进行了研究。结果表明:与模型对照组(0g/kg BW)比较,1.2 g/kg BW剂量组的小鼠血清谷丙转氨酶活力、血清谷草转氨酶活力、肝细胞坏死平均分和肝细胞病变各种类型总平均分均显著降低,受试物对小鼠体重增长无不良影响。
The protective effect of G. lucidum and P. cocos extractive formula on chemical liver injury was studied by a CCL-injuried liver model. The results showed that compared with the control group the mice treated at a dose of 1.2 g/kg BW per day for 30 days were significantly decreased in the activities of serum glutamic-pyruvic transaminase(SGPT)and serum glutamic-oxaloacetic transaminase (SGOT)and the rates of liver cell necrosis and lesions,and their body weight gain was not adversely affected by the extractive formula.
出处
《上海农业学报》
CSCD
北大核心
2012年第3期63-65,共3页
Acta Agriculturae Shanghai
关键词
灵芝
茯苓
提取物组方
化学性肝损伤
保护作用
Ganoderma lucidum
Poris cocos
Extractive formula
Chemical liver injury
Protectiveeffect