摘要
重症肌无力（MG）主要是由乙酰胆碱受体抗体（AChR-Ab）介导，依赖细胞免疫和补体参与的使神经肌肉接头处突触后膜上乙酰胆碱受体受损的自身免疫性疾病。近年来的研究表明，细胞因子间的平衡紊乱与MG的发病有重要关系。因而深入了解不同细胞因子在MG中的作用可以更加明确MG的发病机制及对其治疗提出新的方案。
Myasthenia gravis （MG） is a kind of autoimmune diseases which mainly mediated by the acetylcholine receptor antibody-mediated cellular immunity and the complement involvement, which cause the damage of acetylcholine receptor in the postsynaptic neuromuscular membrane. Recent studies have shown that the cytokine balance disorder has important relationship with the pathogenesis of MG. Extensive research on various cytokines＇ roles in MG helps us better understand the pathogenesis of MG, and formulate new treatment scheme for MG.
出处
《国际免疫学杂志》
CAS
2012年第5期367-370,共4页
International Journal of Immunology
