摘要
[目的]研究蜂蜜、蜂胶外用对深Ⅱ度烫伤模型大鼠创面愈合的影响。[方法]采用YLS-5Q台式超级控温烫伤仪制备大鼠深Ⅱ度烫伤模型。观察蜂蜜、蜂胶外用对烫伤创面愈合的影响,观察创面皮肤组织学变化,检测大鼠血清中羟脯氨酸(HYP)、超氧化物歧化酶(SOD)的含量。[结果]蜂蜜、蜂胶外用能显著提高烫伤大鼠创面愈合率(P<0.01);能显著提高大鼠血清中SOD、HYP含量(P<0.01或P<0.05)。[结论]蜂蜜、蜂胶外用具有明显的促进烫伤创面愈合的作用。
[Objective] To investigate the effects of honey and propolis on wound healing in rats with second-degree scald. [Methods] Second-degree scald on the back of rat was induced by scald-reproducing instrument with super-temperature control （YLS-SQ）. The rates of wound healing and histological changes were observed. The level of hydroxyproline（HYP）and superoxide dismutase （SOD） in serum were determined by ELISA. [Results] The rates of wound healing in treatment group were increased compared with the control group （P〈0.01）. The levels of HYP and SOD in treatment group were higher than that in the control group （P〈0.01 or P〈0.05）. [Conclusion] Honey and propolis has a promoting effect on burn wound healing by its external application.
出处
《天津中医药大学学报》
CAS
2012年第3期154-156,共3页
Journal of Tianjin University of Traditional Chinese Medicine
基金
国家科技支撑计划基金项目(2008BA153B09)
关键词
蜂蜜
蜂胶
外用
烫伤
创面愈合
honey
propolis
external application
scald
wound healing
