摘要
目的验证薰衣草精油芳香疗法的镇静、催眠作用。方法将20只小鼠分为对照组和薰衣草组,熏衣草组分别给予10-3、10-4浓度的薰衣草精油香薰,计数运动时间和运动次数、移动格子数及站立次数。另将30只小鼠分为对照组、薰衣草10-3组和薰衣草10-4组,给予阈剂量戊巴比妥钠诱导睡眠,记录睡眠潜伏期和睡眠时间。结果薰衣草精油香薰后小鼠的运动时间和运动次数少于对照组(P<0.05),移动格子数和站立次数少于对照组(P<0.05);与对照组相比,香薰各组的睡眠潜伏期均缩短(P<0.05),睡眠时间均延长(P<0.01);不同浓度精油香薰的两组相比,睡眠潜伏期没有明显差异(P>0.05),而薰衣草10-3组睡眠时间长于薰衣草10-4(P<0.01)。结论薰衣草精油香薰疗法有镇静催眠作用。
Objective The purpose of this study was to examine the sedative - hypnotic effect of inhaled lavender essential oil. Methods Twenty mice were randomly divided into two groups： control group and lavender group. Mice in lavender group were placed in an inhalation chamber saturated with 10 -3 and 10 -4 density of lavender essential oil for 30 minutes. Animals after inhalation were evaluated for locomotive activity. Other 30 mice were placed in an atmosphere saturated with 10 -3, 10 -4 and 0 density of lavender essential oil, after inhalation, they were evaluated with barbiturate - induced sleeping time. Results In lavender group, locomotion of mice was decreased （ P 〈 0.01 ）, and pentobarbital sleeping time was increased （ P 〈 0.01 ） , sleep latency was shortened （ P 〈 0.05 ）, and mice in 10 -3 and 10 -4 density of lavender essential oil groups had no difference in sleep latency （ P 〉 0.05 ）. Conclusion Inhalation of lavender essential oil for 30 min can induce sedative - hypnotic effect in mice.
出处
《临床和实验医学杂志》
2012年第18期1440-1441,共2页
Journal of Clinical and Experimental Medicine
关键词
薰衣草精油
芳香疗法
镇静催眠
小鼠
动物实验
Lavender essential oil
aromatherapy
Sedative - hypnotic
Mice
Animal experiment
