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冠心病患者超敏C-反应蛋白与颈动脉内中膜厚度检测及相关性分析 被引量：8

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摘要 目的探讨冠心病患者体内炎症反应与颈动脉内中膜厚度的相关性,为其早期诊治及预后判断提供依据。方法研究对象为同期经冠脉造影确诊的冠心病患者262例(冠心病组,其中不稳定型心绞痛168例,稳定型心绞痛94例)及非冠心病患者80例(对照组)。研究对象入院后均检测超敏C-反应蛋白,颈动脉内中膜厚度,并对冠心病组血清hs-CRP及颈动脉内中膜厚度行线性相关分析。结果冠心病组hs-CRP及颈动脉内中膜厚度水平均显著高于对照组(P<0.001),不稳定型心绞痛组hs-CRP及颈动脉内中膜厚度水平均显著高于稳定型心绞痛组(P<0.001);冠心病组血清hs-CRP水平与颈动脉内中膜厚度呈显著正相关(r=0.121,P<0.001)。结论冠心病患者存在慢性炎症反应及颈动脉内膜病变,并且其炎症反应及颈动脉内膜病变呈正相关,及时检测hs-CRP水平及颈动脉内中膜厚度对早期诊治及预后判断具有重要意义。
作者 郭东梅 张易 胡蓉
机构地区 重庆市南川区人民医院心血管内科 西南财经大学体育部 重庆医科大学附属第二医院心血管内科
出处 《重庆医学》 CAS CSCD 北大核心 2012年第23期2408-2410,共3页 Chongqing medicine
关键词 冠心病 超敏C-反应蛋白 颈动脉内中膜厚度
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献15

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同被引文献60

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引证文献8

二级引证文献22

重庆医学
2012年 第23期

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