摘要
【目的】利用超声背向散射积分（IBS）技术评价多发性骨髓瘤（MM）患者肾脏改变。【方法】选取MM患者71例，根据血肌酐水平分为MM无肾损害组（≤173umol／L，45例）及MM肾损害组（〉173μmol／L，26例），选取20例健康者作为对照。观察肾脏长度、体积、皮质与髓质IBS％等指标。【结果】MM无肾损害组肾脏长度、体积及皮质与髓质IBS％均正常，MM肾损害组肾长度及体积较无肾损害者稍减小、肾皮质及髓质IBS％均明显增高。左肾皮质IBS％和左肾髓质IBS％判断MM患者有无肾损害最佳阈值分别为80．1％、67．7％。【结论】MM肾损害患者肾脏稍变小，皮质及髓质IBS0．4均明显增高，利用左肾皮质及髓质IBS％可以较好的评价肾脏损害。
[Objective] To study the ultrasonic integral backscatter for assessing renal changes in patients with multiple myeloma（MM）. [Methods] According to serum creatinine, 71 MM patients were divided into MM with- out renal impairment group（ n=45, ≤173μmol/L） and MM with renal impairment group（ n=26,〉173μmol/ L）. Other 20 healthy people were selected as control group. The parameters such as length and volume of kidney and IBS% of renal cortex and medulla were observed. [Results] The length and volume of kidney and IBS% of re- nal cortex and medulla in MM without renal impairment group were normal. Compared with MM without renal im- pairment group, the length and volume of kidney in MM with renal impairment group slightly decreased, and IBS% of renal cortex and medulla obviously increased. The best threshold of IBS% of cortex and medulla of left kidney for discriminating between MM patients with and without renal impairment was 80. 1% and 67. 7%. [Conclusiol] The length and volume of kidney of MM patients with renal impairment slightly decreases, and IBS% of renal cortex and medulla obviously increase. The IBS% of cortex and medulla of left kidney can well as- sess renal impairment.
出处
《医学临床研究》
CAS
2012年第7期1296-1299,共4页
Journal of Clinical Research
基金
怀化市科技局科技计划项目（编号2011-9-2号）
