期刊文献+

多发性骨髓瘤肾病患者的彩色多普勒超声评价 被引量:7

Color Doppler Ultrasonography Evaluation of Multiple Myeloma with Nephronia
下载PDF
导出
摘要 目的探讨多发性骨髓瘤(MM)肾病患者的肾脏彩色多普勒超声特征。资料与方法选取多发性骨髓瘤患者91例,将血肌酐水平<133μmol/L的55例纳入MMⅠ组,血肌酐≥133μmol/L的36例纳入MMⅡ组,选取无心、肾疾病的25例志愿者作为对照组。观察双肾大小、实质厚度、段动脉和叶间动脉收缩期最大流速(PSV)和阻力指数(RI)并在3组之间进行比较。结果 MMⅡ组双肾长度和实质厚度均小于对照组(P<0.05)和MMⅠ组(P<0.05),MMⅡ组双肾缩小和实质回声增强检出率均高于对照组和MMⅠ组(P<0.05),MMⅠ组实质回声增强检出率高于对照组(P<0.05)。MMⅡ组双肾段动脉及叶间动脉PSV低于对照组及MMⅠ组(P<0.001),双肾段动脉及叶间动脉RI均高于对照组及MMⅠ组(P<0.05),MMⅠ组叶间动脉RI高于对照组(P<0.05)。结论多发性骨髓瘤肾病患者肾脏彩色多普勒特征为实质回声增强,肾脏稍缩小,段动脉和叶间动脉PSV降低及RI升高。 Purpose To investigate color Doppler ultrasonography characteristics of multiple myeloma with nephronia.Materials and Methods Ninety one patients with multiple myeloma and twenty five healthy controls underwent renal color Doppler ultrasonography for kidney length,parenchymal width,peak systolic velocity and resistive index of segmental and interlobar renal arteries.Based on serum creatinine laboratory analyses multiple myeloma patients were divided into normal group(group 1,n =55) and abnormal group(group 2,n =36).Results Group 2 patients showed smaller kidney length and parenchymal width than that in group 1(P 〈 0.05) and control group(P 〈 0.05),and a higher incidence of renal atrophy and parenchyma hyperechogenicity than that in group 1(P 〈 0.05) and control group(P 〈 0.05).The incidence of renal parenchyma hyperechogenicity in group 1 was significantly higher than that in control group(P 〈 0.05).Lower peak systolic velocity and increased resistive index of segmental and interlobar renal artery were found in group 2 than that in group 1 and control group(P 〈 0.05) with increased resistive index of interlobar renal artery in group 1 than that in control group(P 〈0.05).Conclusion Multiple myeloma with nephronia shows a higher incidence of renal parenchyma hyperechogenicity on color Doppler,slightly smaller length of renal,lower peak systolic velocity of segmental and interlobar renal artery,and increases resistive index of segmental and interlobar renal arteries.
出处 《中国医学影像学杂志》 CSCD 北大核心 2011年第7期538-540,共3页 Chinese Journal of Medical Imaging
关键词 多发性骨髓瘤 肾疾病 超声检查 多普勒 彩色 Multiple myeloma; Kidney diseases; Ultrasonography,Doppler,color;
  • 相关文献

参考文献11

二级参考文献43

  • 1王凤凤.探讨影响多发性骨髓瘤肾功能的相关因素[J].中国中西医结合肾病杂志,2000,1(2):103-103. 被引量:4
  • 2侯仰韶,陈泽涛,孟振华,张永奎.多发性骨髓瘤322例误诊资料分析[J].中国实用内科杂志,2005,25(8):757-758. 被引量:15
  • 3章友康.多发性骨髓瘤肾损害[J].中国中西医结合肾病杂志,2006,7(3):125-128. 被引量:18
  • 4Abbott KC, Agodoal LY. Multiple myeloma and light chain-associated nephropathy at end-stage renal disease in the United States: patient characteristics and survival [ J ] Clin Nephrol, 2001,56 : 207 -210. 被引量:1
  • 5Tosi P, Zamagni E. Thalidomide alone or in combination with dexa-methasone in patients with advanced, relapsed or refractory multiple myeloma and renal failure [ J ]. Eur J Haematol,2004,73 (2) : 98 - 103. 被引量:1
  • 6Knudsen LM, Nielsen B. Autologous stem cell transplantation in multiple myeloma: outcome in patients with renal failure [ J ]. Eur J Haemaltol,2005,75 ( 1 ) :27 - 33. 被引量:1
  • 7Sirohi B, Powles R, Kulkami S, et al. Glomerular filtration rate prior to high-dose melphalan 200 mg/m^2 as a surrogate marker of outcome in patients with myeloma [J]. Br J Cancer, 2001,85 ( 3 ) : 325 - 332. 被引量:1
  • 8Ballester OF,Tummala R. High-dose chemotherapy and autologous peripheral blood stem cell transplantation in patients with multiple myeloma and renal insufficiency [ J ]. Bone Marrow Transplant, 1997,20 (80) :653 - 656. 被引量:1
  • 9Nozza A, Siracusano L, Armando S. Bortezomib-dexamethasone combination in a patient with refractory multiple myeloma and impaired renal function [ J ]. Clin Therap,2006,28 ( 6 ) :953 - 959. 被引量:1
  • 10Louise M, Gihad N, Claude K, et al. Plasma exchange in rapidly progressive renal failure due to multiple myeloma:a retrospective case series [ J ]. Am J Nephrol, 1999,19:45 - 50. 被引量:1

共引文献16

同被引文献68

引证文献7

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部